Results 101 to 110 of about 469,357 (267)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Multiple Aliasing of Windowed Real-Valued Signal as a Cause of Accuracy Limitation of DFT Methods

open access: yesIEEE Access
DFT spectral signal analysis is a widely used method for various types of signal processing due to its several advantages. In the case of incoherently sampled real-valued signals, spectral leakage and aliasing occur, causing errors in the signal spectrum
Karel Hajek, Zdenek Kohl
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Accuracy of Frequency Estimation of Structure Vibration under Ambient Excitation: Problems, Causes, and Methods

open access: yesBuildings
Accurate identification of building structure frequencies forms the basis for damage detection. The structural dynamic response signal, under ambient excitation, can be transformed into a superposition of multiple single-frequency exponentially damped ...
Chang Deng   +4 more
doaj   +1 more source

Subspace exploration: Bounds on Projected Frequency Estimation. [PDF]

open access: yesProc ACM SIGACT SIGMOD SIGART Symp Princ Database Syst, 2021
Cormode G, Dickens C, Woodruff DP.
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

TrEMOLO: accurate transposable element allele frequency estimation using long-read sequencing data combining assembly and mapping-based approaches. [PDF]

open access: yesGenome Biol, 2023
Mohamed M   +7 more
europepmc   +1 more source

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