Results 111 to 120 of about 540,085 (315)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Performance Optimization in Frequency Estimation of Noisy Signals: Ds-IpDTFT Estimator. [PDF]

Sensors (Basel), 2023
Wei M, Zhu Y, Sun J, Lu X, Mu X, Xu J.
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Modeling a Small-size Unmanned Helicopter Using Optimal Estimation in The Frequency Domain

, 2008
In this paper, a semi-decoupled state space model of a small-size helicopter is developed for hovering conditions in order to simplify the model identification process.
Qi JT(齐俊桐), Dai L(戴磊), Song DL(宋大雷), Liu GJ(刘光军), Han JD(韩建达)   +4 more
core  

An Efficient Modal Parameter Identification Method Based on Free Vibration Response and the Energy Sorted Matrix Pencil Method [PDF]

International Journal of Railway Research
Modal parameter identification of railway bridges is essential for comprehending their dynamic behavior. This understanding enables the development of numerical simulations that more accurately mirror their actual behavior.
Mohammad Sadegh Ayubirad, Shervan Ataei
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Frequency Domain Modeling of High Voltage Transformers Using a Nonlinear Least-Square Estimation Technique

, 2009
The development of transformer models can be achieved based on experimental frequency response measurements providing access to the windings is available and the physical dimensions are known in order to calculate R, L and C parameter values. Of interest
Mohamed, R, Lewin, P L
core  

A Novel Sparse Framework for Angle and Frequency Estimation. [PDF]

Sensors (Basel), 2022
Zhao G, Huang D, Cai C, Wu P.
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Conditionally Efficient Estimation of Long-run Relationships Using Mixed-frequency Time Series [PDF]

I analyze efficient estimation of a cointegrating vector when the regressand is observed at a lower frequency than the regressors. Previous authors have examined the effects of specific temporal aggregation or sampling schemes, finding conventionally ...
J. Isaac Miller
core