Results 131 to 140 of about 540,085 (315)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

On the Estimation of Forest Vertical Structure From Multibaseline Polarimetric SAR Data

open access: yes, 2012
Forest characterization and biomass estimation by means of remote sensing systems are nowadays “hot topics” within the remote sensing community, given their importance in the terrestrial carbon budget. In fact, forest vertical structure is a key variable
Pardini, Matteo   +11 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Fundamental Frequency Estimation for Noisy Speech Using Entropy-Weighted Periodic and Harmonic Features [PDF]

open access: yes, 2004
This paper proposes a robust method for estimating the fundamental frequency (F0) in real environments. It is assumed that the spectral structure of real environmental noise varies momentarily and its energy does not distribute evenly in the time ...
ISHIZUKA, Kentaro   +3 more
core  

Coherent shift estimation for stacks of SAR images

open access: yes, 2011
Speckle tracking is used with SAR images to estimate displacements, in ways that support or integrate interferometric measurements. This paper derives Fisher information expressions for the displacement estimation using coherent speckle tracking, for the
De Zan, Francesco, Francesco De Zan
core   +1 more source

Optimality of Frequency Moment Estimation

open access: yesProceedings of the 57th Annual ACM Symposium on Theory of Computing
Estimating the second frequency moment of a stream up to $(1\pm\varepsilon)$ multiplicative error requires at most $O(\log n / \varepsilon^2)$ bits of space, due to a seminal result of Alon, Matias, and Szegedy. It is also known that at least $Ω(\log n + 1/\varepsilon^{2})$ space is needed.
Mark Braverman, Or Zamir
openaire   +3 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Frequency Synchronization plus Channel Estimation by Least Squares Approach for OFDM in Frequency-Selective Channels

open access: yes, 2013
Applying the least squares technique, we perform frequency synchronization and channel estimation by using repeated identical blocks of training data for orthogonal frequency division multiplexing (OFDM) systems in frequency-selective channels.
Liu, Hong-Yu   +1 more
core   +1 more source

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