Results 141 to 150 of about 540,085 (315)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Nonparametric estimation of the volatility under microstructure noise: wavelet adaptation

open access: yes
We study nonparametric estimation of the volatility function of a diffusion process from discrete data, when the data are blurred by additional noise. This noise can be white or correlated, and serves as a model for microstructure effects in financial ...
Hoffmann, Marc   +2 more
core  

Robust-momentum-learning-rate-based adaptive fractional-order least mean squares approach for power system frequency estimation using chaotic Harris hawks optimization

open access: yesFrontiers in Energy Research
A novel robust adaptive technique is proposed to estimate the instantaneous power system frequency using a momentum-learning-control-rate-based fractional-order least mean squares approach with enhanced Harris hawks optimization.
Subhranshu Sekhar Pati, Umamani Subudhi
doaj   +1 more source

Subspace exploration: Bounds on Projected Frequency Estimation. [PDF]

open access: yesProc ACM SIGACT SIGMOD SIGART Symp Princ Database Syst, 2021
Cormode G, Dickens C, Woodruff DP.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A new frequency offset estimation for OFDM-based systems

open access: yes, 2006
A new carrier frequency offset estimation scheme in orthogonal frequency division multiplexing (OFDM) is proposed. The scheme includes coarse frequency offset estimation and fine frequency offset estimation.
Xiao, WN (Xiao, Wanang)   +7 more
core  

Parallel-Interference-Cancellation-Assisted Decision-Directed Channel Estimation for OFDM Systems using Multiple Transmit Antennas

open access: yes, 2005
The number of transmit antennas that can be employed in the context of least-squares (LS) channel estimation contrived for orthogonal frequency division multiplexing (OFDM) systems employing multiple transmit antennas is limited by the ratio of the ...
M. Munster   +3 more
core   +1 more source

Robust Band-Pass Filter-Based PLL-Less Approach for Three-Phase Nonsinusoidal Grid Conditions

open access: yesIEEE Open Journal of Instrumentation and Measurement
The performance enhancement of an inverter-based grid-connected system necessitates a fast and accurate dynamic response in terms of estimating three-phase grid voltage attributes.
Manish Kumar   +8 more
doaj   +1 more source

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