Results 171 to 180 of about 540,085 (315)

A No-Arbitrage Approach to Range-Based Estimation of Return Covariances and Correlations [PDF]

We extend the important idea of range-based volatility estimation to the multivariate case. In particular, we propose a range-based covariance estimator that is motivated by financial economic considerations (the absence of arbitrage), in addition to ...
Michael W. Brandt, Francis X. Diebold
core  

Fully automatic peak frequency estimation of the posterior dominant rhythm in a large retrospective hospital EEG cohort. [PDF]

Clin Neurophysiol Pract, 2021
Zibrandtsen IC, Kjaer TW.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Residual Asymmetry Modeling and Joint Time-Frequency Estimation for High-Dynamic Two-Way Microwave Links. [PDF]

Sensors (Basel)
Hao Z, Wu H.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Iterative Amplitude Equalization for Frequency Estimation (IAE-DFT). [PDF]

Sensors (Basel)
Serea E, Donciu C, Temneanu MC.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Generic MMSE Decision Directed Channel Estimation for OFDM and MC-CDMA

, 2004
In this letter we propose a Minimum Mean Square Error (MMSE) Channel Impulse Response (CIR) estimator-aided Decision Directed Channel Estimation (DDCE) method, which is suitable for employment in both OFDM and MC-CDMA systems.
Akhtman, Jos, Hanzo, Lajos
core  

DEP-track: a motion-aware framework for large-scale cell tracking and crossover frequency estimation in dielectrophoresis. [PDF]

Front Bioinform
Lee S, Choi S, Lee Y, Bae H, Han J, Kim YS, Lee SW, Yang S.   +7 more
europepmc   +1 more source