Results 181 to 190 of about 540,085 (315)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Bioacoustic fundamental frequency estimation: a cross-species dataset and deep learning baseline. [PDF]

open access: yesBioacoustics
Best P   +19 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Robust Frequency Offset Estimation of OFDM Systems

open access: yes, 2007
儘管正交分頻多工對干擾敏感,但仍被廣泛的應用在無線寬頻通訊系統中。在窄頻干擾下,首先研究其在同步碼符號輔助之下的時間與頻率偏移估測的效果。同時,時頻交錯正交分頻多工被普遍擬用在(相對地)受到窄頻干擾的環境下所操作的超寬頻通訊系統。這篇論文,主要是在利用時頻交錯的協助,發展出在干擾環境下有效的頻率偏估測方法。正交分頻多工系統經由不同的次頻帶的同步碼符號,在時域,使用適應性雜訊消除法技術來估測消除干擾後的關聯樣本;在頻域,透過頻域轉換去取得關聯次載波,使得所估測的頻率偏移更為強健 ...
Sun, Kin-Man, 孫健文
core  

Home - About - Disclaimer - Privacy