Results 171 to 180 of about 1,160,559 (367)

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

The Influence of Temperature on Frequency Modulation Spectroscopy in Atom Gravimeter. [PDF]

open access: yesSensors (Basel), 2022
Weng K   +6 more
europepmc   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Low Conducted-EMI Single-Phase Boost PFC with Sliding Frequency Modulation. [PDF]

open access: yesConf Proc (IEEE Appl Power Electron Conf Expo), 2023
Akhmetov Z, Abdelraziq M, Pantic Z.
europepmc   +1 more source

PWM strategy with harmonics injection and modulated frequency triangular carrier. A review [PDF]

open access: yesarXiv
A new, programmed pulse width modulation (PWM) technique to control power inverters, which uses a harmonic injection modulator and a frequency modulated triangular carrier, synchronized with the modulating signal is presented in this paper. The instantaneous carrier frequency is adjusted according to a periodic function synchronized with the ...
arxiv  

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