Results 151 to 160 of about 377,227 (256)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Neural modelling of the encoding of fast frequency modulation. [PDF]

PLoS Comput Biol, 2021
Tabas A, von Kriegstein K.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Secondary Frequency Modulation Strategy for SiC Inverters Based on Periodic Spread Spectrum Modulation. [PDF]

Sensors (Basel)
Cao Y, Su J, Yan Y, Lin Z, Shi T.
europepmc   +1 more source

Visualization of Electrolyte Reaction Field Near the Negative Electrode of a Lead Acid Battery by Means of Amplitude/Frequency Modulation Atomic Force Microscopy. [PDF]

Materials (Basel), 2023
Suzuki Y, Imamura Y, Katsube D, Kogure A, Hirai N, Kimura M.   +5 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Deciphering temporal scales of visual awareness: insights from flicker frequency modulation in continuous flash suppression. [PDF]

Neurosci Conscious
Singhal I, Srinivasan N.
europepmc   +1 more source

Separating microparticles by material and size using dielectrophoretic chromatography with frequency modulation. [PDF]

Sci Rep, 2021
Giesler J, Weirauch L, Thöming J, Baune M, Pesch GR.   +4 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

An analytic, efficient and optimal readout algorithm for compact interferometers based on deep frequency modulation. [PDF]

Sci Rep
Eckhardt T, Gerberding O.
europepmc   +1 more source