Results 1 to 10 of about 5,106,399 (296)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Precision Construction of Chiral Optical Fields with Nine Controllable Degrees of Freedom

open access: yesAdvanced Photonics Research
Recently, chiral optical fields (COFs) have garnered significant attention due to their multiple controllable degrees of freedom (DOFs), enabling applications in diverse areas such as optical tweezers, manufacturing, and holographic encryption.
Duo Deng   +4 more
doaj   +1 more source

QUEST: A Simulation-Based QKD Architecture with Eight-State Time-Bin Modulation and Adaptive Homodyne–Heterodyne Detection

open access: yesInformation
Quantum key distribution (QKD) employs quantum states to generate shared cryptographic keys. An attacker interacting with the modeled non-orthogonal quantum signals can affect the monitored statistics, and hence they can be detected under the specified ...
Vidhya Prakash Rajendran   +4 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Fast Non-Mechanical Beam Steering via Cascaded Stressed Polymer Network Liquid Crystal Optical Switch and Liquid Crystal Polarization Grating

open access: yesPhotonics
Non-mechanical beam steering technology based on liquid crystal optical switches and liquid crystal polarization gratings holds significant application prospects in fields such as laser communication, radar detection, and optical information processing ...
Jiahui Chen   +5 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Laser-induced speckle scatter patterns in Bacillus colonies

open access: yesFrontiers in Microbiology, 2014
Label-free bacterial colony phenotyping technology called BARDOT (BActerial Rapid Detection using Optical scattering Technology) provided successful classification of several different bacteria at the genus, species, and serovar level. Recent experiments
Huisung eKim   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

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