Results 131 to 140 of about 6,346,538 (309)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Segmented discrete polynomial-phase transform with coprime sampling

The Journal of Engineering, 2019
Segmented discrete polynomial-phase transform (DPT) integrates input signals to enable detection and parameter estimation of weak linear frequency modulated (LFM) signals.
Shengheng Liu, Yahui Ma, Tao Shan
doaj   +1 more source

Rake Receiver Detection of Adaptive Modulation Aided CDMA over Frequency Selective Channels

, 2001
A closed form Bit Error Ratio (BER) formula is derived for a fixed-mode Quadrature Amplitude Modulation (QAM) scheme employing Rake receivers and receiver antenna diversity.
Choi, B.J., Hanzo, L.
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Simulation study on the frequency modulation of sawtooth oscillation by plasma shape in tokamak

Nuclear Fusion
This study numerically investigates the impact of the tokamak plasma shape (elongation, triangularity, and aspect ratio) on the amplitude and period of sawtooth oscillations using the three-dimensional toroidal nonlinear magnetic fluid code CLT and the ...
Peijie Zhang, Jinhong Yang, Zhenzhen Ren, Zheng Xiao, Jiaxuan Chu, Jun Kuang, Weihua Wang   +6 more
doaj   +1 more source

Ground clutter simulation for airborne forward-looking multi-channel LFMCW radar

The Journal of Engineering, 2019
Ground clutter is a crucial factor that affects the detection performance of the airborne forward-looking multi-channel linear frequency modulated continuous wave (LFMCW) radar, so the distribution characteristics of studying the ground clutter plays an ...
Hai Li, Jialing Duan, Di Song
doaj   +1 more source

Soft Decoding Assisted Interference Cancellation in a Non-Binary LDPC Coded Fast Frequency Hopping Multiuser System Using Product Combining [PDF]

, 2007
In this contribution, soft-input-soft-output (SISO) decoding aided successive interference cancellation (SIC) is considered in fast frequency hopping (FFH), M-ary frequency shift keying (MFSK) using product combining (PC), when operating in multiple ...
Lie-Liang Yang, Ahmed, S, Guo, F, Yang, L-L, Hanzo, L, Lajos Hanzo, Feng Guo, Sohail Ahmed   +7 more
core   +1 more source

Frequency modulation of ERK activation dynamics rewires cell fate

Molecular Systems Biology, 2015
Transient versus sustained ERK MAP kinase (MAPK) activation dynamics induce proliferation versus differentiation in response to epidermal (EGF) or nerve (NGF) growth factors in PC‐12 cells.
H. Ryu, M. Chung, M. Dobrzyński, D. Fey, Y. Blum, Sung Sik Lee, M. Peter, B. Kholodenko, N. Jeon, O. Pertz   +9 more
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Hydrostatic Asymmetric Journal Gas Barings for Seismic ACROSS Transmitters

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2007
The ACROSS (Accurately Controlled Routinely Operated Signal System) is used to detect subtle changes in the physical state of Earth's structure. The signal is sinusoidal elastic waves generated by the rotation of a rotor with eccentric mass set in ...
Tomohiko ISE, Takao TORII, Nobuyoshi MORITA, Shinichi TOGO, Makoto OKANO   +4 more
doaj   +1 more source