Results 91 to 100 of about 14,434,014 (273)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Routine Testing–Oriented Method for Evaluating Inductive Current Transformers Accuracy Under Harmonic Distortion, Based on Maximum Current Error and Phase Displacement

IEEE Access
In the case of the modern inductive current transformers the most important factor that have influence on their wideband accuracy is the self-distortion of the secondary current caused by the nonlinearity of the magnetization characteristic of the ...
Michal Kaczmarek
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Dynamic Energy Sparse Self-Attention Based on Informer for Remaining Useful Life of Rolling Bearings

IEEE Access
Predicting the remaining useful life of rolling bearings presents significant challenges due to their nonstationary degradation patterns. Conventional methods struggle with long sequences and are strongly dependent on manual feature extraction, which can
Cheng Shi, Qifei Li, Hui Chen, Yuanwei Song, Qianqi Le   +4 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Comparing the Accuracy and Sensitivity of Mesh-Free and Finite Element Methods in Vibration Analysis

Dynamics
This paper uses the flexural vibration of cantilever beams as a benchmark problem to test mesh-free and finite element methods in structural dynamics. First, a symbolic analysis of the “kernel collocation” type mesh-free method is carried out, in which ...
Majid Aleyaasin
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Vector Signals and Invariant Systems: Re-Tooling Linear Systems Theory

Signals
In a previous work, we identified the importance of rotation invariance in the standard complex-valued theory of linear time-invariant (LTI) systems and proposed a generalized vector-valued (VV) definition of convolution that reinterprets the complex ...
Mamta Dalal, Steven Sandoval
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Research on fault localization of distribution transformers based on frequency response analysis and support vector machine (SVM)

Frontiers in Energy Research
Distribution transformers are vital to the stability of the power system, but long-term operation and environmental factors can cause distribution transformers to discharge, posing a potential threat.
Xingting Liu, Haiqi Wang, Zhuo Gao, Xutao Han   +3 more
doaj   +1 more source