Results 91 to 100 of about 2,213,154 (301)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Frequency response computation for complex structures with damping and acoustic fluid
, 2004 textModal frequency response analysis is a very economical approach for large and complex structural systems since there is an enormous reduction in dimension from the original finite element frequency response problem to the number of modes ...
Kim, Chang-wan, 1969-
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Asking difficult questions: task complexity increases the impact of response alternatives
, 1992 Bless H, Bohner G, Hild T, Schwarz N. Asking difficult questions: task complexity increases the impact of response alternatives. European Journal of Social Psychology.
Hild, Traudel +11 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A choice reaction time analysis of spatial frequency discrimination [PDF]
, 1989 Simple reaction time to the onset of sinewave gratings was measured as a function of spatial frequency in two observers. These results are compared to the choice reaction time required for the observer to correctly discriminate the spatial frequency of ...
Greenlee, Mark W., Breitmeyer, B. G.
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Frequency-Power Control of VSWTG for Improved Frequency Regulation
, 2023 With increasing wind energy penetration and impending grid codes, it is important to enable wind-based power plants to provide sensitive frequency response in grids that may experience irregular frequency fluctuations with noise induced.
Asma Aziz (13059384) +1 more
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Analysis of the dynamic responses of SOA wavelength converters using linear frequency resolved gating technique [PDF]
, 2008 This letter demonstrates the applicability of the linear frequency resolved optical gating technique for the complete characterization of the fast dynamic response of semiconductor optical amplifiers (SOAs) when operating as wavelength converters.
Perez-Pardo, A. +4 more
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