Results 101 to 110 of about 29,705,142 (291)

Low and high frequency model of three phase transformer by frequency response analysis measurement

open access: yesOpen Physics, 2018
The behavior analysis of the transformer is usually achieved by the frequency response analysis (FRA), which is obtained by the application of a very low AC voltage in over a wide frequency range.
Chaouche Moustafa Sahnoune   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An optical fibre-based frequency dissemination network for Australia

open access: yes, 2011
An optical-fibre network is being planned for distribution of optical and microwave reference frequencies in Australia. This network would connect a number of research facilities and the National Measurement Institute (NMI), allowing long-range ...
Luiten, A.   +9 more
core   +1 more source

Dynamic Characteristics and Vibration Behavior of SKL-15 Rail Fastening Clip in High-Speed Railway Systems

open access: yesApplied Sciences
Current research on the vibration characteristics of fastener clips primarily employs modal experiments combined with finite element simulations; however, limited attention has been given to the dynamic vibration behavior of clips during actual train ...
Yunpeng Li   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Supercapacitor Model with Charge-Dependent Parameters Based on Experimental Frequency Response

open access: yesSensors
The characterization of supercapacitors (SCs), particularly electric double-layer capacitors (EDLCs), is useful for the design of energy management systems.
Carlos Gilabert-Torres   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A Novel Adaptive Multiple-Image-Feature Fusion Method for Transformer Winding Fault Diagnosis

open access: yesEng
Frequency response analysis (FRA) is recognized as an effective method in power transformer winding fault diagnosis. However, the traditional numerical index methods focus on the overall features of FRA curves, making it difficult to capture subtle ...
Huan Peng   +5 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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