This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Vibration reduction strategies based on wave propagation phenomena, such as generating band gaps in periodic structures, are attracting attention in the field of mechanical engineering. This paper investigates how the structural and material compositions
Shoya HONDA +4 more
doaj +1 more source
Algorithmic options for joint time-frequency analysis in structural dynamics applications [PDF]
The purpose of this paper is to present recent research efforts by the authors supporting the superiority of joint time-frequency analysis over the traditional Fourier transform in the study of non-stationary signals commonly encountered in the fields of
Giaralis, A. +2 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Frequency Response Analysis: An Overview of the Measurement Process and Interpretation of Results for Fault Diagnosis and Location in Power Transformers [PDF]
One of the main components of a power transformer is the transformer insulation system, namely, transformer insulation oil and transformer insulation paper. Any failure can cause the transformer to fail temporarily or permanently.
Hamed Shadfar, Hamid Reza Izadfar
doaj +1 more source
FREQ: A computational package for multivariable system loop-shaping procedures [PDF]
Many approaches in the field of linear, multivariable time-invariant systems analysis and controller synthesis employ loop-sharing procedures wherein design parameters are chosen to shape frequency-response singular value plots of selected transfer ...
Armstrong, Ernest S., Giesy, Daniel P.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Low and high frequency model of three phase transformer by frequency response analysis measurement
The behavior analysis of the transformer is usually achieved by the frequency response analysis (FRA), which is obtained by the application of a very low AC voltage in over a wide frequency range.
Chaouche Moustafa Sahnoune +2 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source

