Results 191 to 200 of about 1,837,906 (265)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Numerical analysis of three-dimensional middle ear and inner ear based on nonlinear and viscoelastic constitutive relations. [PDF]

Mechanobiol Med
Yao W, Wang J, Ye J.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Noninvasive Electrophysiological Biomarkers of Olfactory Responses Across Cognitive States in Alzheimer Dementia: Cross-Sectional Study. [PDF]

JMIR Mhealth Uhealth
Ha J, Bok J, Lee Y, Kim YS, Kim JS, Kim HJ, Jang Y.   +6 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Data-Driven Inverse Design Enables a Dexterous Hand with Human-Comparable Dynamic Performance in Structured Tasks. [PDF]

Biomimetics (Basel)
Jiang L, Lan K, Liu X, Fu C, Jin Y, Wang H.   +5 more
europepmc   +1 more source

ANALYSIS OF THE SPURIOUS FREQUENCY RESPONSE OF MIXERS.

, 1969
openaire   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Magnetoencephalography biomarkers for assessing myelin content and neuronal function in acute optic neuritis. [PDF]

Brain Commun
Beigneux Y, Gitton C, Anwar AR, Lemarechal JD, Hamzaoui M, Paques M, Vignal C, Audo I, Bodini B, Stankoff B, Leocani L, Lubetzki C, George N, Louapre C.   +13 more
europepmc   +1 more source

Efficient distribution of tuned mass dampers for seismic control in regular and irregular multi-story steel buildings. [PDF]

Sci Rep
Shabib MM, Farag HM, Khalifa YA, Zahran MS.   +3 more
europepmc   +1 more source