Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Modal response characterizations and mechanism separation modeling of amphibious vehicle body under different water entry depths. [PDF]
Li G +6 more
europepmc +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
A Non-Contact Electrostatic Potential Sensor Based on Cantilever Micro-Vibration for Surface Potential Measurement of Insulating Components. [PDF]
Chen C +6 more
europepmc +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Sound frequency predicts the bodily location of auditory-induced tactile sensations in synesthetic and ordinary perception. [PDF]
Koenig L, Ro T.
europepmc +1 more source
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Identifying Optimal Thresholds for Early Opioid Use Frequency in Predicting Buprenorphine Outcomes. [PDF]
Votaw VR +3 more
europepmc +1 more source
Efficacy and Safety of Clobazam Adjunctive Therapy in Pediatric Patients with Drug-Resistant Epilepsy. [PDF]
Yu L +9 more
europepmc +1 more source

