Results 121 to 130 of about 1,329,156 (311)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Hybrid Sensor Placement Framework Using Criterion-Guided Candidate Selection and Optimization

Sensors
This study presents a hybrid sensor placement methodology that combines criterion-based candidate selection with advanced optimization algorithms. Four established selection criteria—modal kinetic energy (MKE), modal strain energy (MSE), modal assurance ...
Se-Hee Kim, JungHyun Kyung, Jae-Hyoung An, Hee-Chang Eun   +3 more
doaj   +1 more source

Fuel Cell Frequency Response Function Modeling for Control Applications

, 2010
This paper provides the framework for first-order transfer function modeling of a fuel cell for controls use. It is shown that under specific conditions a fuel cell can be modeled as a first-order system.
Cunningham, Patrick, Thomas C. H. Roberts, Patrick J. Cunningham, Roberts, T.   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The Accuracy of Frequency Response Function Measurements Using FFT-Based Analyzers With Transient Excitation

, 1986
The accuracy of the frequency response measurement obtained using impact excitation and a Fast Fourier Transform based spectrum analyzer has been investigated.
P. Cawley
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Identification of mechanical parameters of fiber-reinforced composites by frequency response function approximation method. [PDF]

Sci Prog, 2020
Li H, Xue P, Rong W, Li X, Wen B.
europepmc   +1 more source

Computation of transfer function data from frequency response data with application to data-based root-locus

, 2015
This paper describes the computation and use of transfer function data (TFD) computed from frequency response data of a system. TFD can be regarded as a sampled, data-based representation of the transfer function.
van de Molengraft, M.J.G.; id_orcid, van de Molengraft, M.J.G., Steinbuch, M., Hoogendijk, R., den Hamer, A.J., Angelis, G.Z., Steinbuch, M.; id_orcid   +6 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Uncertainty Quantification Analysis of Dynamic Responses in Plate Structures Based on a Physics-Informed CVAE Model

Applied Sciences
The propagation of uncertainties in structural dynamic responses, arising from variations in material properties, geometry, and boundary conditions, is of critical concern to researchers in a variety of engineering instances.
Shujing Tang, Xuewen Yin, Wenwei Wu
doaj   +1 more source