Results 101 to 110 of about 14,112,739 (302)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Frequency response of gas turbine condition monitoring system

open access: yes, 1999
The work reported in this thesis is concerned with the Condition Monitoring by using Generalised Frequency Response Function. Two types of nonlinear models are discussed but the attention is focussed on a nonlinear model called NARX (Nonlinear ...
Mohd. Taib, Mohd. Nor
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The selected inputs and parameters of the Hill function and frequency response curves of the nonlinear ARX model.

open access: yes, 2013
The selected inputs and parameters of the Hill function and frequency response curves of the nonlinear ARX model.
Takaho Tsuchiya (385046)   +4 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The frequency-dependent directivity of a planar Fabry-Perot polymer film ultrasound sensor [PDF]

open access: yes, 2007
A model of the frequency-dependent directivity of a planar, optically-addressed, Fabry-Perot (FP), polymer film ultrasound sensor is described and validated against experimental directivity measurements made over a frequency range of 1 to 15 MHz and ...
Beard, PC, Cox, BT
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Computation of transfer function data from frequency response data with application to data-based root-locus

open access: yes, 2015
This paper describes the computation and use of transfer function data (TFD) computed from frequency response data of a system. TFD can be regarded as a sampled, data-based representation of the transfer function.
van de Molengraft, M.J.G.; id_orcid   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The frequency-response electroretinogram distinguishes cone and abnormal rod function in rd12 mice.

open access: yes, 2015
Early studies on Rpe65 knockout mice reported that remaining visual function was attributable to cone function. However, this finding has been challenged more and more as time has passed.
Ying He   +17 more
core   +1 more source

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