Results 131 to 140 of about 1,293,707 (300)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Frequency Domain Modeling of High Voltage Transformers Using a Nonlinear Least-Square Estimation Technique

open access: yes, 2009
The development of transformer models can be achieved based on experimental frequency response measurements providing access to the windings is available and the physical dimensions are known in order to calculate R, L and C parameter values. Of interest
Mohamed, R, Lewin, P L
core  

Frequency-Dependent Antioxidant Responses in HT-1080 Human Fibrosarcoma Cells Exposed to Weak Radio Frequency Fields

open access: yesAntioxidants
This study explores the complex relationship between radio frequency (RF) exposure and cancer cells, focusing on the HT-1080 human fibrosarcoma cell line.
Hakki Gurhan, Frank Barnes
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Uncomfortable images produce non-sparse responses in a model of primary visual cortex

open access: yes, 2015
The processing of visual information by the nervous system requires significant metabolic resources. To minimize the energy needed, our visual system appears to be optimized to encode typical natural images as efficiently as possible.
Hibbard, Paul B.   +4 more
core   +1 more source

Transfer Reconstruction from High-Frequency to Low-Frequency Bridge Responses Under Vehicular Loading with a ResNet

open access: yesApplied Sciences
The reconstruction of bridge responses has been a significant area of focus within the field of structural health monitoring. This process entails the cross-reconstruction of responses from various cross-sections to identify any anomalies at specific ...
Xuzhao Lu   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

CONVOLUTIONAL CODES AND FREQUENCY RESPONSES

open access: yes, 2008
. Frequency responses are introduced as objects that are much finer than transfer functions, and their investigation is carried out via convolutional codes.
V. Lomadze
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Tax Burden and GDP: Evidence from Frequency Doman Approach for the USA [PDF]

open access: yes
We employed Breitung and Candelon's (2006) frequency domain approach to investigate the short-and long-run Granger-causality from different tax burden to GDP in the USA for the period 1947:1 –2009:3.
Aviral Kumar Tiwari
core  

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