Results 111 to 120 of about 1,293,707 (300)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Subjective and biodynamic responses of seated subjects exposed to whole-body vertical vibration at low frequency

open access: yes, 2014
As the magnitude of vertical whole-body vibration increases, the resonance frequency in the apparent mass of the human body reduces and there are changes in the frequency-dependence of acceleration equivalent comfort contours.
Zhou, Zhen
core  

ANALYSIS OF ELECTRONIC DEVICES FREQUENCY RESPONSES USING SET METHOD

open access: yesМіжнародний науково-технічний журнал "Проблеми керування та інформатики", 2006
The methodology is proposed for calculation frequency responses the electronic devices. The device are described with the help of the system of linear equations with uncertainty of the coefficients and the right side which are put in the form of set of ...
V.P. Evtushok
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Frequency of household interview responses.

open access: yes, 2015
*We were informed during Interview #6 of 23 that deworming of pigs was a universal practice in the village. Thus, we began explicitly asking this question in every subsequent household interview, totaling 18 responses.Frequency of household interview ...
Alexis Medina (305158)   +5 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A FEM-Based Method Using Harmonic Overtones to Determine the Effective Elastic, Dielectric, and Piezoelectric Parameters of Freely Vibrating Thick Piezoelectric Disks

open access: yes, 2013
To gain an understanding of the electroelasticproperties of tactile piezoelectric sensors used in the characterizationof soft tissue, the frequency-dependent electric impedanceresponse of thick piezoelectric disks has been calculatedusing finite element ...
Andersson, Britt M.   +5 more
core   +1 more source

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