Results 101 to 110 of about 1,981,461 (291)

Rotor Vibration Caused by Oil Whip and Treatment Method

open access: yesJixie chuandong, 2020
The basic concepts and main characteristics of the oil whirl and oil whip are introduced, and the oil whip may cause serious damage to the unit, which must be paid great attention to and dealt with in time.
Yufeng Li   +4 more
doaj  

Temporal variations in the acoustic signal from faculae

open access: yes, 2012
The integrated brightness of the Sun shows variability on time-scales from minutes to decades. This variability is mainly caused by pressure mode oscillations, by granulation and by dark spots and bright faculae on the surface of the Sun.
Aigrain   +37 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Synthetic Amplitude Spectrum and Its Extensions for Analyzing the Two Perpendicular Directional Vibration Displacement Signals of a Rotating Rotor

open access: yesAdvances in Mechanical Engineering, 2013
Classical Amplitude Spectrum analysis and Full Amplitude Spectrum analysis exhibit deficiencies in analyzing the two perpendicular directional vibration displacement signals of a rotating rotor.
Liang Yonggang   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Study on interference problems between 5G base stations and adjacent frequency systems

open access: yesDianxin kexue, 2021
For the interference problems in frequency sharing and geographical coexistence between 5G base stations and the adjacent frequency systems such as satellite earth stations, the different situations consisting of the interferences to 5G base stations and
Jianming YAO
doaj   +2 more sources

A stochastic approach for deriving effective linear properties of bilinear hysteretic systems subject to design spectrum compatible strong ground motions [PDF]

open access: yes, 2011
A novel statistical linearization based approach is proposed to derive effective linear properties (ELPs), namely damping ratio and natural frequency, for bilinear hysteretic oscillators subject to seismic excitations specified by an elastic response ...
Giaralis, A.   +2 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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