Results 111 to 120 of about 14,764,212 (352)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A frequency-domain approach to the analysis of stability and bifurcations in nonlinear systems described by differential-algebraic equations [PDF]
, 2007 A general numerical technique is proposed for the assessment of the stability of periodic solutions and the determination of bifurcations for limit cycles in autonomous nonlinear systems represented by ordinary differential equations in the differential ...
Bonani, Fabrizio +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Kongzhi Yu Xinxi JishuOn April 28, 2025, a large-scale power outage occurred across the Iberian Peninsula and parts of southern France, seriously affecting local social production and people's normal lives.
ZHANG Wuqi +4 more
doaj
Joint Time and Frequency Dissemination Network Over Delay-Stabilized Fiber Optic Links
IEEE Photonics Journal, 2015 A precise fiber-based time and frequency dissemination scheme for multiple users with a tree-like branching topology is proposed. Through this scheme, ultrastable signals can be easily accessed online without affecting other sites.
Wei Chen +6 more
doaj +1 more source
Rotor angle stability with high penetrations of wind generation [PDF]
, 2012 This paper explores the relationship between wind generation, particularly the control of reactive power from variable speed wind turbine generators, and the rotor angle stability of the conventional synchronous generators in the system.
O\u27Malley, Mark +6 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source