Results 111 to 120 of about 6,200,319 (299)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Gradient descent based dynamic optimization for VSG dominated microgrid
The Journal of EngineeringAs the integration of distributed generation units into the power grid continues to grow, the system becomes increasingly vulnerable to power fluctuations and potential failures, which significantly challenge grid stability.
Yan Li +5 more
doaj +1 more source
Implications for Frequency Stability and Reserve Requirements
peer reviewedThe global energy transition, driven by the Sustainable Development Goals and commitments to decarbonization, is transforming power systems with a rapid shift towards renewable energy sources.
Navia Orellana, Marco Antonio +3 more
core
, 2014 Large-scale integration of non-inertial generators such as wind farms will create frequency stability issues due to reduced system inertia. Inertia based frequency stability study is important to predict the performance of power system with increased ...
J. McLoughlin +5 more
core +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Low‐head pumped hydro storage: An evaluation of energy balancing and frequency support
IET Renewable Power GenerationLarge‐scale energy storage solutions are crucial to ensure grid stability and reliability in the ongoing energy transition towards a low‐carbon, renewable energy based electricity supply.
Justus Peter Hoffstaedt +6 more
doaj +1 more source