Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Pulsed optically pumped Rb clock with high frequency stability performances
In this paper we present a prototype of Rb clock working in pulsed regime with high freq stability performances. In particular, a frequency stability as low as 1.6×10-13τ -1/2 has been measured for integration times up to 105 s.
MICALIZIO, SALVATORE +5 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Stiffness and strength of shear diaphragms used for stability bracing of slender beams [PDF]
Structural Stability Research Council Annual Stability Conference 2014, SSRC 2014; Toronto, ON; Canada; 25 March 2014 through 28 March 2014Light gage metal decking is often used in structures as concrete deck formwork, roof cladding or siding.
Vardaroğlu, Mustafa +2 more
core +1 more source
Gradient descent based dynamic optimization for VSG dominated microgrid
As the integration of distributed generation units into the power grid continues to grow, the system becomes increasingly vulnerable to power fluctuations and potential failures, which significantly challenge grid stability.
Yan Li +5 more
doaj +1 more source
Implications for Frequency Stability and Reserve Requirements
peer reviewedThe global energy transition, driven by the Sustainable Development Goals and commitments to decarbonization, is transforming power systems with a rapid shift towards renewable energy sources.
Navia Orellana, Marco Antonio +3 more
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Low‐head pumped hydro storage: An evaluation of energy balancing and frequency support
Large‐scale energy storage solutions are crucial to ensure grid stability and reliability in the ongoing energy transition towards a low‐carbon, renewable energy based electricity supply.
Justus Peter Hoffstaedt +6 more
doaj +1 more source
An Inertia Reserve Capacity Planning Method for Power Systems Considering Risk Preference
The traditional reserve planning method implicitly includes inertia in the frequency response reserve without realizing separate and accurate planning for inertia reserve, and cannot consider the risk preference of the decision maker, which leads to the ...
Na Zhang +5 more
doaj +1 more source
Due to a rapid increase in the utilization of power converter-based renewable energy sources (RESs), the overall system inertia in an interconnected power system might be significantly reduced, increasing the vulnerability of the interconnected power ...
T. Kerdphol +2 more
semanticscholar +1 more source

