Results 151 to 160 of about 186,401 (311)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Frequency stabilization and noise-induced spectral narrowing in resonators with zero dispersion. [PDF]

Nat Commun, 2019
Huang L, Soskin SM, Khovanov IA, Mannella R, Ninios K, Chan HB.   +5 more
europepmc   +1 more source

On the control aspect of laser frequency stabilization

, 1991
Realization of frequency stable lasers is viewed as key to progress in many areas of research; therefore, the search for more effective techniques of frequency stabilization has intensified significantly in recent years.
Zia, Omar
core  

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Exploring the synergic effect of thermal tuning and mode-coupling for frequency stabilization in micromechanical resonators. [PDF]

Microsyst Nanoeng
Xiao Y, Sun C, Liu S, Wu G.
europepmc   +1 more source

Ramsey-Bordé Matter-Wave Interferometry for Laser Frequency Stabilization at 10^{-16} Frequency Instability and Below. [PDF]

Phys Rev Lett, 2019
Olson J, Fox RW, Fortier TM, Sheerin TF, Brown RC, Leopardi H, Stoner RE, Oates CW, Ludlow AD.   +8 more
europepmc   +1 more source

Workplace for stabilization of laser frequency

, 2003
This paper describes a new appliance for demonstration of frequency stabilization of a laser diode. That is an original solution which is appointed for hands-on teaching students of optoelectronic courses. The arrangement consists of a laser diode driver,
Buchta, Zdeněk
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source