Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Frequent Pattern Mining for IoT Big Streaming Data Based on Short-Pattern Graph
Big Data Mining and AnalyticsInternet of things (IoT) technology is important in the era of big data, and in most IoT scenarios, data are constantly arriving in the form of streams.
Guang Yang, Xia Wu, Jing Zhang
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Frequent spatiotemporal trajectory pattern mining based on pheromone concentration
, 2013 With the development of positioning technologies (GPS, GSM networks, etc.), the real time data of mobile objects becomes increasingly available. It is leading to new opportunity of discovering behavior pattern and useful knowledge automatically in ...
Wang L(王亮) +3 more
core
The Mining Algorithm of Maximum Frequent Itemsets Based on Frequent Pattern Tree. [PDF]
Comput Intell Neurosci, 2022 Mi X.
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Revisiting Local Descriptors via Frequent Pattern Mining for Fine-Grained Image Retrieval. [PDF]
Entropy (Basel), 2022 Zheng M, Geng Y, Li Q.
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A frequent max substring technique for Thai text indexing
, 2011 This research details the development of a novel methodology, called the frequent max substring technique, for extracting indexing terms and constructing an index for Thai text documents.
Chumwatana, Todsanai
core
Applying the FAIR4Health Solution to Identify Multimorbidity Patterns and Their Association with Mortality through a Frequent Pattern Growth Association Algorithm. [PDF]
Int J Environ Res Public Health, 2022 Carmona-Pírez J +18 more
europepmc +1 more source