Results 171 to 180 of about 1,878,751 (279)

Pseudo-Left Ventricular Summit Premature Ventricular Contraction in a Patient With Abnormal Intraventricular Conduction. [PDF]

JACC Case Rep
Pham Nhu H, Nguyen The Nam H, Nguyen Xuan T, Nguyen Van D, Pham Van T.   +4 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Exercising alone in men and group exercise in women are cross-sectionally associated with positive mental health among older Japanese. [PDF]

Environ Health Prev Med
Tomioka K, Shima M, Saeki K.
europepmc   +1 more source

Efficient frequent pattern mining

, 2002
... In this thesis we focus on the Frequent Pattern Discovery task and how it can be efficiently solved in the specific context of itemsets and association rules. The original motivation for searching association rules came from the need to analyze so called supermarket transaction data, that is, to examine customer behavior in terms of the purchased ...
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Clinical characteristics analysis of pertussis and Mycoplasma pneumoniae infection in children. [PDF]

Front Cell Infect Microbiol
Xue M, Wei X, Wang B, Liu M, Zhang Y, Ma X.   +5 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Frequent Pattern Mining of Eye-Tracking Records Partitioned into Cognitive Chunks

Applied Computational Intelligence and Soft Computing, 2014
Noriyuki Matsuda, Haruhiko Takeuchi
doaj   +1 more source

Variable shift work in family medicine residents is associated with a non-dipper pattern and reduced phase angle: possible adaptive blood pressure mechanisms and body composition imbalance. [PDF]

Front Cardiovasc Med
Cardoso-Peña E, Garduño-García JJ, Benítez-Arciniega AD, Bustamante-Hernández MB, Oros-Pantoja R, Soto-Piña AE.   +5 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source