Results 141 to 150 of about 23,652 (302)

Mining Maximal Generalized Frequent Geographic Patterns with Knowledge Constraints

open access: yes, 2006
In frequent geographic pattern mining a large amount of patterns is well known a priori. This paper presents a novel approach for mining frequent geographic patterns without associations that are previously known as non-interesting.
Vania Bogorny   +11 more
core   +1 more source

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

open access: yesAdvanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

open access: yesAdvanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu   +10 more
wiley   +1 more source

Periodic Pattern Mining a Algorithms and Applications

open access: yes, 2013
Owing to a large number of applications periodic pattern mining has been extensively studied for over a decade Periodic pattern is a pattern that repeats itself with a specific period in a give sequence Periodic patterns can be mined from datasets like
Shashi Mogalla   +2 more
core  

Analyzing Efficient Algorithms of Frequent Pattern Mining

open access: yes, 2012
Frequent pattern mining has been playing an important role for analyzing data in various fields such as medical treatment, biology, finance, networks, and so on.
Lee, Gangin   +5 more
core   +1 more source

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

open access: yesAdvanced Science, EarlyView.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma   +22 more
wiley   +1 more source

Beyond d‐Band Catalysis: A Critical Review and Descriptor Framework for Rare‐Earth Engineering in Lithium–Sulfur Batteries

open access: yesAdvanced Science, EarlyView.
Rare‐earth catalysts regulate lithium–sulfur battery chemistry through f‐orbital–mediated interactions, enabling simultaneous polysulfide adsorption and catalytic conversion on conductive carbon hosts. This synergistic control suppresses the shuttle effect, accelerates redox kinetics, and guides stable Li2S nucleation, providing a mechanistic framework
Fan Wang   +5 more
wiley   +1 more source

Application of gap-constraints given sequential frequent pattern mining for protein function prediction. [PDF]

open access: yesOsong Public Health Res Perspect, 2015
Park HA   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy