Results 51 to 60 of about 23,652 (302)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Frequent contiguous pattern mining over biological sequences of protein misfolded diseases

BMC Bioinformatics, 2021
Background Proteins are integral part of all living beings, which are building blocks of many amino acids. To be functionally active, amino acids chain folds up in a complex way to give each protein a unique 3D shape, where a minor error may cause ...
Mohammad Shahedul Islam, Md. Abul Kashem Mia, Mohammad Shamsur Rahman, Mohammad Shamsul Arefin, Pranab Kumar Dhar, Takeshi Koshiba   +5 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

A frequent pattern mining algorithm for feature extraction of customer reviews [PDF]

, 2012
Online shoppers often have different idea about the same product. They look for the product features that are consistent with their goal. Sometimes a feature might be interesting for one, while it does not make that impression for someone else ...
Ibrahim, Roliana, Ghorashi, Seyed Hamid, Noekhah, Shirin, Dastjerdi, Niloufar Salehi   +3 more
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Mining frequent closed itemsets with the frequent pattern list [PDF]

Proceedings 2001 IEEE International Conference on Data Mining, 2002
The mining of a complete set of frequent itemsets will lead to a huge number of itemsets. Fortunately, this problem can be reduced to the mining of frequent closed itemsets (FCIs), which results in a much smaller number of itemsets. The approaches to mining frequent closed itemsets can be categorized into two groups: those with candidate generation and
Tseng, Fan-Chen, Hsu, Ching-Chi, Chen, Henry   +2 more
openaire   +2 more sources

Selecting Feature Subsets in Continuous Flow Network Attack Traffic Big Data Using Incremental Frequent Pattern Mining

Algorithms
This work focuses on finding frequent patterns in continuous flow network traffic Big Data using incremental frequent pattern mining. A newly created Zeek Conn Log MITRE ATT&CK framework labeled dataset, UWF-ZeekData24, generated using the Cyber Range at
Sikha S. Bagui, Andrew Benyacko, Dustin Mink, Subhash C. Bagui, Arijit Bagchi   +4 more
doaj   +1 more source

Graph-based pattern identification from architecture change logs [PDF]

, 2012
Service-based architectures have become commonplace, creating the need to address their systematic maintenance and evolution. We investigate architecture change representation, primarily focusing on the identification of change patterns that support the ...
Pooyan Jamshidi (5276344), Pooyan Jamshidi, Ahmad, Aakash, Aakash Ahmad, Claus Pahl, Claus Pahl (12588787), Pahl, Claus, Jamshidi, Pooyan, Aakash Ahmad (5022314)   +8 more
core   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Mining XML Frequent Query Patterns [PDF]

, 2007
With XML being the standard for data encoding and exchange over Internet, how to find the interesting XML query characteristic efficiently becomes a critical issue. Mining frequent query pattern is a technique to discover the most frequently occurring query pattern trees from a large collection of XML queries.
Cheng Hua, Hai-jun Zhao, Yi Chen
openaire   +1 more source