Results 121 to 130 of about 4,248,745 (299)
Discover EnvironmentClimate variability, characterised by erratic rainfall patterns and frequent droughts, poses a significant threat to crop and livestock production in arid and semi-arid regions.
Sileshi Tolesa Ejeta +3 more
doaj +1 more source
arules - A Computational Environment for Mining Association Rules and Frequent Item Sets [PDF]
Mining frequent itemsets and association rules is a popular and well researched approach for discovering interesting relationships between variables in large databases.
Bettina Grün +2 more
core
Regularly frequent patterns mining from sensor data stream
, 2013 Mining interesting and useful knowledge from the huge amount of data gathered in wireless sensor networks is a challenging task. Works reported in literature use support metric-based sensor association rule which employs the occurrence frequency of ...
Iqbal Gondal +5 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Frequent feature combination patterns within each category.
, 2019 Frequent feature combination patterns within each category.
Jiahua Du (7834748) +4 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
MINING CONCISE REPRESENTATIONS OF FREQUENT HIGH-UTILITY OCCUPANCY ITEMSETS USING GENERATOR PATTERNS
Tạp chí Khoa học Đại học Đà LạtA current trend in data mining is the discovery of frequent high-utility occupancy itemsets (FHUOIs) in quantitative databases. These itemsets capture user preferences and significantly contribute to transaction utility, making them valuable for real ...
Van Hai Duong +2 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Discovering frequent tree patterns over data streams
, 2012 [[abstract]]Since tree-structured data such as XML files are widely used for data representation and exchange on the Internet, discovering frequent tree patterns over tree-structured data streams becomes an interesting issue. In this paper, we propose an
Hsieh, Mark Cheng-Enn;Wu, Yi-Hung;Chen, Arbee L. P.
core