Results 141 to 150 of about 4,248,745 (299)
Flexible and Feasible Support Measures for Mining Frequent Patterns in Large Labeled Graphs. [PDF]
Proc ACM SIGMOD Int Conf Manag Data, 2017 Meng J, Tu YC.
europepmc +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Similarity evaluation of DNA sequences based on frequent patterns and entropy. [PDF]
BMC Genomics, 2015 Xie X, Guan J, Zhou S.
europepmc +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Hyper-structure mining of frequent patterns in uncertain data streams. [PDF]
Knowl Inf Syst, 2013 Hewanadungodage C, Xia Y, Lee JJ, Tu YC.
europepmc +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Mining Frequent Trajectory Patterns
, 2013 本論文提出三個探勘移動軌跡樣式的演算法: GBM、 FTM 及LTM。GBM 尋找由空間中連續的格點組成的樣式，而格點間的時間延遲則由時間間隔代表。FTM 探勘彈性移動軌跡樣式，其中樣式的格點不一定要連續，格點間的時間延遲則以區段代表。雖然以點序列來描述軌跡可以有效降低雜訊以及簡化整個探勘的程序；但亦可能產生過長的樣式，以致於需要耗費大量的時間進行探勘的工作。因此，LTM利用連續的線段代表物體的移動軌跡，它可以有效的降低記憶體的耗用、樣式的長度與頻繁樣式的數量，進而提升探勘的效率 ...
Chen, Yi-An, 陳怡安
core
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source