Results 101 to 110 of about 6,167,253 (291)

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Spectrum : RPI Fresh Water Institute

, 2011
A video feature from the early 1980s on the work of the Darrin Freshwater ...
LeClair, Susan Tepper, Boylen, Charles W.   +1 more
core   +1 more source

Elucidating the effects of heavy metals contamination on vital organ of fish and migratory birds found at fresh water ecosystem. [PDF]

Heliyon, 2023
Khan BN, Ullah H, Ashfaq Y, Hussain N, Atique U, Aziz T, Alharbi M, Albekairi TH, Alasmari AF.   +8 more
europepmc   +1 more source

1998 General Assembly Legislation Related to Water

, 1998
The Virginia General Assembly held its regular session from January 14 to March 17, then reconvened April 22-23 to respond to the governor’s vetoes.
Manfre, Joseph, Virginia Water Resources Research Center   +1 more
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Polyphasic Identification of Distoseptispora with Six New Species from Fresh Water. [PDF]

J Fungi (Basel), 2022
Zhang H, Zhu R, Qing Y, Yang H, Li C, Wang G, Zhang D, Ning P.   +7 more
europepmc   +1 more source

Water-related Legislation in the 2002 Virginia General Assembly

, 2002
In 2002, the Virginia General Assembly convened on January 9 and adjourned on March 9, with a reconvened (“veto”) session on April 17. The legislature considered 2907 bills; 1587 were passed, 804 failed, and 517 were carried over to the 2003 session ...
Virginia Water Resources Research Center
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Proppant Distribution Prediction between Perforation Clusters Using Fresh Water in a Horizontal Wellbore. [PDF]

ACS Omega, 2023
Alajmei S.
europepmc   +1 more source

Fresh Water

, 1973
Contained within the 4th Edition (1974) of the Atlas of Canada is a map that shows the area of fresh water. It is split into squares that have the percentage of total fresh water. Each square covers an area of 10,000 square kilometers. According to the map, fresh water bodies occupy 7.9% of the area of Canada.
openaire   +1 more source