Results 151 to 160 of about 2,301,881 (356)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Persisting at the Edge of Ecological Collapse: The Impact of Urbanization on Fish and Amphibian Communities From Lake Xochimilco

open access: yesEnvironmental DNA
Freshwater ecosystems are globally threatened by habitat loss, pollution, and invasive species, all of which are particularly acute in urban areas. To assess the impacts of urbanization on freshwater biodiversity—specifically the effects of alien species
Alejandro Maeda‐Obregon   +12 more
doaj   +1 more source

Occurrence of Dendrocephalus brasiliensis Pesta, 1921 (Crustacea, Anostraca) in the Caras river, southern Ceara, Brazil

open access: yesAnais da Academia Brasileira de Ciências
Occurrence of Dendrocephalus brasiliensis Pesta, 1921 (Crustacea, Anostraca) in the Caras river, southern Ceara, Brazil. The specimens were collected in March and April 2014. The new occurrence extends the distribution and update area of occupancy of the
FRANCISCO R.V. FREITA   +4 more
doaj   +1 more source

Fresh-Water Mollusks as Biomonitors for Ecotoxicity of Nanomaterials. [PDF]

open access: yesNanomaterials (Basel), 2021
Abramenko N   +4 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Effect of Cypermethrin on Blood Hematology and Biochemical Parameters in Fresh Water Fish Ctenopharyngodon idella (Grass Carp). [PDF]

open access: yesCell Mol Biol (Noisy-le-grand), 2022
Ullah M   +12 more
europepmc   +1 more source

Management of Fresh water Fisheries [PDF]

open access: yes, 1999
The book under review 'Management of Fresh Water Fisheries' by Jacques Arrignon is a very valuable compendium of knowledge on fresh water fisheries presented in three parts, such as ecological fundamentals, fish breeding and management of aquatic media.
Menon, N G
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Fresh water production from atmospheric air: Technology and innovation outlook. [PDF]

open access: yesiScience, 2021
Peeters R   +3 more
europepmc   +1 more source

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