Results 81 to 90 of about 2,216,642 (344)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Spatiotemporal dynamics of microbial communities and cyanobacteria blooms in two North American Lakes using long-read 16S rRNA sequencing

open access: yesEcological Indicators
Understanding spatial and temporal heterogeneity in ecosystems is essential to forecasting the effects of environmental changes. Freshwater microbes, including cyanobacteria, play a crucial role in food-web structures and biochemical processes, yet can ...
Manuel Castro Berman   +6 more
doaj   +1 more source

Salinity Effects on Strategies of Glycogen Utilization in Livers of Euryhaline Milkfish (Chanos chanos) under Hypothermal Stress

open access: yesFrontiers in Physiology, 2018
The fluctuation of temperature affects many physiological responses in ectothermic organisms, including feed intake, growth, reproduction, and behavior.
Chia-Hao Chang   +6 more
doaj   +1 more source

Fresh Water Production in Coastal and Remote Areas by Solar Powered Liquid-liquid Membrane Contactor [PDF]

open access: yes, 2003
Liquid-liquid membrane contactor (LLMC) is a new desalination process using microporous hydrophobic membrane. The temperature difference at two solution-membrane interfaces gives rise to a trans membrane vapor pressure difference that drives the flux. In
Susanto, H. (Heru), Wenten, I. G. (I)
core  

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Revue bibliographique - Principales caractéristiques de l'élevage de l'omble chevalier (Salvelinus alpinus L.) en eau douce

open access: yesKnowledge and Management of Aquatic Ecosystems, 1992
L'omble chevalier (Salvelinus alpinus L.) est un salmonidé d'eau froide. Ses caractéristiques physiologiques et biologiques étant différentes de celles des autres poissons de la même famille, les pratiques d'élevage ne sont pas identiques. Les principaux
GUILLARD J., GILLET C., CHAMPIGNEULLE A.
doaj   +1 more source

Improving New Zealand water governance: challenges and recommendations [PDF]

open access: yes, 2014
The overwhelming majority of New Zealand’s exports – not least agricultural and horticultural – require water, and in large quantities. Indeed, in many respects water is New Zealand’s largest export.
Elizabeth Eppel
core   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Priorities for, and preferred approaches to, management of New Zealand fresh waters [PDF]

open access: yes
Since 2000 six standardised biennial public surveys of the state of the New Zealand environment have been undertaken. A fresh water case study was included in the 2010 postal survey and in an electronic survey.
Cullen, Ross   +3 more
core   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

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