Results 91 to 100 of about 1,105,287 (296)
Correlative intravital imaging of cGMP signals and vasodilation in mice
Cyclic guanosine monophosphate (cGMP) is an important signaling molecule and drug target in the cardiovascular system. It is well known that stimulation of the vascular nitric oxide (NO)-cGMP pathway results in vasodilation.
Martin eThunemann +6 more
doaj +1 more source
Antibacterial photodynamic therapy (a-PDT) has emerged as a promising non-invasive therapeutic modality that utilizes the combination of a photosensitive agent, molecular oxygen, and excitation light to generate reactive oxygen species (ROS ...
A. A. Matiushkina (17014077) +8 more
core +1 more source
A FRET-Based Calcium Biosensor with Fast Signal Kinetics and High Fluorescence Change [PDF]
Genetically encoded calcium biosensors have become valuable tools in cell biology and neuroscience, but some aspects such as signal strength and response kinetics still need improvement. Here we report the generation of a FRET-based calcium biosensor employing troponin C as calcium-binding moiety that is fast, is stable in imaging experiments, and ...
Mank, Marco +5 more
openaire +4 more sources
Laser‐Induced Graphene from Waste Almond Shells
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova +9 more
wiley +1 more source
An ATP-Driven N Protein-DDX21 Molecular Switch Dynamically Controls SARS-CoV-2 RNA G-Quadruplex Heterogeneity. [PDF]
An ATP‐driven molecular switch, comprising viral nucleocapsid (N) protein and host helicase DDX21, dynamically modulates SARS‐CoV‐2 RNA G‐quadruplex (G4) heterogeneity. These viral G4s feature non‐canonical ion‐dependence and act as energy‐sensitive structural checkpoints.
Zheng YT +8 more
europepmc +2 more sources
Interpreting Crowding Effects on FRET Signals for Protein Kinetics Analysis [PDF]
In biological studies in vitro and in vivo, techniques involving Förster resonance energy transfer (FRET) and FRET quantification use the interaction of CyPet-SUMO1 and its E2 ligase, YPet-Ubc9, to determine the dissociation constant (KD).
Hsieh, Mandy
core +1 more source
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen +3 more
wiley +1 more source
Förster resonance energy transfer (FRET) between two molecules in nanoscale distances is utilized in significant number of applications including biological and chemical applications, monitoring cellular activities, sensors, wireless communications ...
Gorkem Memisoglu +3 more
doaj +1 more source
The binding efficiency of peptide analogs at 10 μM in the FRET competitive binding assay.
High FRET signals indicate no binding, whereas low FRET signals indicate binding. Peptide analog 15 exhibits significant binding affinity at 10 μM, in contrast to the remaining analogs. *, p < 0.0005.
Aloysius Wilfred Raj Arokiaraj (2549401) +8 more
core +1 more source
ABSTRACT Chitosan, a polysaccharide upcycled from biowaste, has long promised sustainable, biocompatible, and antimicrobial films and devices, an appeal reinforced by its recent regulatory recognition, with several chitosan‐based antibacterial dressings gaining clearance through the Food and Drug Administration's 510(k) pathway.
Jacopo Nicoletti +16 more
wiley +1 more source

