Results 51 to 60 of about 58,185 (266)
Numerical Model for Hydration-Lubricated Contact and Its Friction Behavior at Nanoscale
Frontiers in Mechanical Engineering, 2020 In this study, we propose a numerical model to investigate the contact and friction behaviors of hydration-lubricated contact in an aqueous solution confined in a gap of several molecular diameters.
Yanfei Fang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Analysis of Wear Behavior Between Tire Rubber and Silicone Rubber
Applied SciencesVulcanized NR-SBR is widely used in vehicle components; however, its irreversible crosslinking limits recyclability and contributes to the large number of tires discarded annually worldwide, and in this context, this work presents an experimental ...
Juana Abenojar +2 more
doaj +1 more source
Study on the Nano-Friction Behavior of Nickel-Based Ag Film Composites Based on Molecular Dynamics
Lubricants, 2023 The nano-friction behavior of nickel-based Ag film composites was evaluated using molecular dynamics simulations. The mechanical properties, the surface morphology, the migration behavior of Ag atoms and the defect evolution during repeated friction were
Wenbang Chen +6 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Friction and Deformation Behavior of Elastomers
Materials Sciences and Applications, 2019 This research paper is about investigating the mechanisms of elastomeric friction at low velocities. To do so, different experimental setups were performed to analyze friction, adhesion and surface energy among others. The tested materials were EPDM samples with variations in the carbon black content. It was found, that at least for low velocities, the
Alexander Adam +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Holistic Measurement of the Friction Behavior of Wet Clutches
LubricantsThe safe and efficient torque transmission of wet disk clutch systems requires high coefficients of friction. To achieve good controllability and high comfort, a positive slope of the coefficient of friction over sliding velocity is ensured by a ...
Patrick Strobl +5 more
doaj +1 more source
Shock and Vibration, 2016 The objective of the study is to examine the quantitative influence of end friction on the dynamic mechanical behavior of concrete under medium and low strain rates.
Liu Jin +3 more
doaj +1 more source