Results 41 to 50 of about 84,351 (313)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Friction Analysis on Scratch Deformation Modes of Visco-Elastic-Plastic Materials [PDF]

, 2012
Understanding of abrasion resistance and associated surfaces deformation mechanisms is of primary importance in materials engineering and design. Instrumented scratch testing has proven to be a useful tool for characterizing the abrasion resistance of ...
D.J. , Schipper, J. , Jamari, I. , Syafaat, Budi , Setiyana   +3 more
core  

Friction and Wear Behavior of Ti-6Al-7Nb Biomaterial Alloy [PDF]

, 2013
Titanium has been increasingly applied to biomedical application because of its improved mechanical characteristics, corrosion resistance and biocompatibility. However their application remains limited, due to the low strength and poor wear resistance of
LABAIZ, Mohamed, DEKHIL, Leila, ASSALA, Omar, IOST, Alain, Iost, Alain A., FELLAH, Mamoun   +5 more
core   +1 more source

FRICTION AND WEAR BEHAVIOR OF SELECTED DENTAL CERAMICS

Surface Review and Letters, 2009
The purpose of this study was to determine the friction coefficients and wear rates of six commercially available dental ceramics including IPS Empress 2 (E2), Cergo Pressable Ceramic (CPC), Cercon Ceram (CCS) and Super porcelain EX-3 (SPE). Bovine enamel (BE) was also tested as a reference material for comparison purposes.
Park, Jongee, Pekkan, Gurel, Ozturk, Abdullah   +2 more
openaire   +4 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Multi-physics simulation of friction stir welding process

, 2009
Purpose: The Friction Stir Welding (FSW) process comprises of several highly coupled (and non-linear) physical phenomena: large plastic deformation, material flow transportation, mechanical stirring of the tool, tool-workpiece surface interaction ...
Robert Hamilton, Li, Hongjun, Hongjun Li, Hamilton, Robert, Mackenzie, D., Mackenzie, Donald, Hamilton, R., Donald MacKenzie   +7 more
core   +1 more source

Analysis of Frictional Effects on the Dynamic Response of Gear Systems and the Implications for Diagnostics [PDF]

, 2015
To develop accurate diagnostic techniques, this study examines gear dynamic responses based on a model including the frictional effect of tooth mesh process.
Gu, Fengshou, Brethee, Khaldoon F., Ball, Andrew, Fengshou Gu, Andrew D. Ball, Ball, Andrew D., Jingwei Gao, Gao, Jingwei, Khaldoon F. Brethee   +8 more
core   +1 more source

Frictional Behavior of Natural Granite Gouges at Hydrothermal Conditions With Varied Initial Grain Size

Geophysical Research Letters
Fine‐grained gouge found in fault cores controls earthquake generation through its frictional behavior and microstructural evolution. Here we present friction experiments on natural granitic gouges of various initial grain sizes at hydrothermal ...
Huiru Lei, Yongsheng Zhou, André R. Niemeijer, Jianye Chen, Christopher J. Spiers   +4 more
doaj   +1 more source

Cross Scale Tribological Behavior of Textured High-Entropy Alloy Coatings

Lubricants
This paper presents a cross-scale model for predicting the tribological behavior of textured coatings made of high-entropy alloys. The research methodology includes molecular dynamic modeling, a modified fractal surface model, and the Green’s method with
Yazhou Mao, Linlin Guo, Aoya Wang, Ruiyi Ma, Zixuan Wangan   +4 more
doaj   +1 more source

Numerical Model for Hydration-Lubricated Contact and Its Friction Behavior at Nanoscale

Frontiers in Mechanical Engineering, 2020
In this study, we propose a numerical model to investigate the contact and friction behaviors of hydration-lubricated contact in an aqueous solution confined in a gap of several molecular diameters.
Yanfei Fang, Liran Ma, Xianzhang Wang, Jianbin Luo   +3 more
doaj   +1 more source