Results 21 to 30 of about 70,487 (267)

Temperature effects on the nano-friction across exposed atomic step edges

open access: yesAIP Advances, 2020
Despite the practical and fundamental importance of friction, there are many issues that are still needed to be explored and revealed; one of them is how friction changes across an atomic surface step edge at different temperatures.
Wen Wang, Ashu Wang, Lingyan Zeng
doaj   +1 more source

Tunneling with the Lorentz force and the friction [PDF]

open access: yesPhysica Scripta, 1997
We present a semiclassical study of a transport process, the tunneling, in the presence of a magnetic field and a dissipative environment. We have found that the problem can be mapped onto an effective one-dimensional one, and the tunneling rate is strongly affected by the magnetic field, such as a complete suppression by a large parallel magnetic ...
openaire   +2 more sources

Friction Force Microscopy

open access: yesMaterials Today, 2005
This chapter introduces Friction Force Microscopy, which is possibly the most important experimental technique in nanotribology. In spite of the apparent simplicity of this technique, a special care is required in the calibration of the force sensors, as discussed in the chapter.
openaire   +1 more source

Probing of Nanoscale Friction and Mechanical Characteristics of Cotton Fiber’s Surface

open access: yesFibers, 2019
The surface topography and nanomechanical attributes of two samples of cotton fibers, namely, A and B, were characterized with various operation modes of an Atomic Force Microscope (AFM).
Farzad Hosseinali   +1 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Friction of two-dimensional colloidal particles with magnetic dipole and Lennard–Jones interactions: A numerical study

open access: yesFriction, 2019
We use Langevin simulations to study the sliding friction of two-dimensional colloidal particles on a substrate with randomly distributed point-like pinning centers.
Zhongying Zhang   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Resultant Normal Contact Force-Based Contact Friction Model for the Combined Finite-Discrete Element Method and Its Validation

open access: yesMathematics, 2023
In the conventional FDEM (Combined Finite and Discrete Element Method), each contact pair might have multiple contact points where friction forces are applied, leading to non-unique friction force assignments and potentially introducing computational ...
He Liu   +5 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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