Results 201 to 210 of about 24,842 (306)

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

open access: yesChemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow   +2 more
wiley   +1 more source

Automated Process Optimization in a Novel Triple Shaft Mixer with Adaptive Mixing Modes

open access: yesChemie Ingenieur Technik, EarlyView.
A novel multi‐purpose mixer with adjustable blade angle and a coaxial stirrer is developed, providing three degrees of freedom. An optimization strategy is integrated to autonomously identify optimal operating conditions through automated tests. The current draw of the main stirrer serves as the optimization criterion, while stirrer speeds, directions,
B. Schwarz, H. Kniele, J. A. Lindner
wiley   +1 more source

Dissimilar Aluminium Alloys Welding by Friction Stir Processing and Reverse Rotation Friction Stir Processing

open access: yesIOP Conference Series: Materials Science and Engineering, 2018
Muhsin J Jweeg   +3 more
openaire   +1 more source

Double Sided Traction Force Microscopy: A Method to Confine Cells for Physiologically Relevant Force Measurements

open access: yesCytoskeleton, EarlyView.
ABSTRACT In this paper we describe a technique to make a confined environment of variable stiffness that is suitable for high‐resolution live‐cell imaging. This versatile and adaptable technique enables cell confinement between soft elastic surfaces made from polyacrylamide gels.
Alexia Caillier, Patrick W. Oakes
wiley   +1 more source

Investigation on hard‐rock breaking performance and auxiliary mechanism of picks assisted with both‐sided high‐pressure water jets

open access: yesDeep Underground Science and Engineering, EarlyView.
This paper investigates the high‐pressure water jet‐pick combined rock‐breaking mode (HPC), which employs high‐pressure water jets to precut grooves on both sides of the picks. The rock‐breaking patterns and performance of the HPC method are obtained, and the auxiliary rock‐breaking mechanism of water jet grooving is revealed.
Jingjing Lu   +6 more
wiley   +1 more source

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