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2000
Abstract Friedreich’s ataxia is an autosomal-recessive disease with a prevalence of between 1 and 2 per 100,000, characterized by symptoms and signs including progressive ataxia, absent tendon reflexes in the legs, distal impairment of position and vibration sense, Babinski reflexes, and dysarthria.
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Abstract Friedreich’s ataxia is an autosomal-recessive disease with a prevalence of between 1 and 2 per 100,000, characterized by symptoms and signs including progressive ataxia, absent tendon reflexes in the legs, distal impairment of position and vibration sense, Babinski reflexes, and dysarthria.
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Archives of Neurology & Psychiatry, 1938
After Friedreich (1863 1 ) described the form of ataxia which bears his name, the clinical and pathologic features of the morbid condition which he established were the subject of much controversy. Thus, Friedreich and Schultze 2 considered it a disease of the spinal cord (combined degeneration), while Senator, 3 on purely clinical grounds, looked on ...
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After Friedreich (1863 1 ) described the form of ataxia which bears his name, the clinical and pathologic features of the morbid condition which he established were the subject of much controversy. Thus, Friedreich and Schultze 2 considered it a disease of the spinal cord (combined degeneration), while Senator, 3 on purely clinical grounds, looked on ...
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Archives of Neurology & Psychiatry, 1927
Although reports of the occurrence of Friedreich's ataxia in siblings are not uncommon, rarely has an opportunity been presented for the clinical study during the different stages of the disease and of the spinal cord lesions in such cases. The cases here described were those of two brothers, fullblooded negroes, each of whom was 8 years of age when ...
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Although reports of the occurrence of Friedreich's ataxia in siblings are not uncommon, rarely has an opportunity been presented for the clinical study during the different stages of the disease and of the spinal cord lesions in such cases. The cases here described were those of two brothers, fullblooded negroes, each of whom was 8 years of age when ...
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2012
Friedreich’s ataxia (FRDA) is the most common of the autosomal recessive cerebellar ataxias. According to the Harding’s criteria, FRDA begins before the end of puberty or at least before the age of 25. The FRDA gene encodes frataxin, a protein which is involved in mitochondrial iron regulation.
Roongroj Bhidayasiri, Daniel Tarsy
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Friedreich’s ataxia (FRDA) is the most common of the autosomal recessive cerebellar ataxias. According to the Harding’s criteria, FRDA begins before the end of puberty or at least before the age of 25. The FRDA gene encodes frataxin, a protein which is involved in mitochondrial iron regulation.
Roongroj Bhidayasiri, Daniel Tarsy
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