Results 21 to 30 of about 92,917 (264)

Neuropathologic basis of frontotemporal dementia in progressive supranuclear palsy. [PDF]

, 2019
BackgroundProgressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by neuronal loss in the extrapyramidal system with pathologic accumulation of tau in neurons and glia.
Dickson, Dennis W, Duara, Ranjan, Graff-Radford, Neil R, Josephs, Keith A, Litvan, Irene, Murray, Melissa E, Sakae, Nobutaka, Uitti, Ryan J, Wszolek, Zbigniew K   +8 more
core   +1 more source

A case of familial frontotemporal dementia caused by a progranulin gene mutation

Clinical Parkinsonism & Related Disorders, 2023
After Alzheimer’s disease, Frontotemporal dementia (FTD) is the most common cause of early-onset dementia. Several genetic mutations have been identified in familial FTD, with mutations in progranulin (GRN) accounting for approximately 20–25% of familial
Lauryn Currens, Nigel Harrison, Maria Schmidt, Halima Amjad, Weiyi Mu, Sonja W. Scholz, Jee Bang, Alexander Pantelyat   +7 more
doaj   +1 more source

Phenocopy syndrome of frontotemporal dementia

European Psychiatry, 2021
Introduction Frontotemporal dementia (FTD) is a group of neurodegenerative disorders characterized by behavioral or language changes with progressive executive dysfunction. It´s subdivided into two variants, the behavioral and language variants.
D. Martins, R. Faria, M. Pinho, S. Rodrigues   +3 more
doaj   +1 more source

Apraxia profiles—A single cognitive marker to discriminate all variants of frontotemporal lobar degeneration and Alzheimer's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018
Introduction Apraxia is common in neurodegenerative dementias but underrepresented in clinical workup for differential diagnoses. Methods Praxis‐profiles were assessed with the Dementia Apraxia Test in 93 patients with early stages of biologically ...
Andreas Johnen, Sophia Reul, Heinz Wiendl, Sven G. Meuth, Thomas Duning   +4 more
doaj   +1 more source

Terra incognita—cerebellar contributions to neuropsychiatric and cognitive dysfunction in behavioral variant frontotemporal dementia [PDF]

, 2015
Although converging evidence has positioned the human cerebellum as an important relay for intact cognitive and neuropsychiatric processing, changes in this large structure remain mostly overlooked in behavioral variant frontotemporal dementia (bvFTD), a
Emma eDevenney, Emma eDevenney, Glenda M Halliday, Glenda M Halliday, John R Hodges, John R Hodges, John R Hodges, Matthew C Kiernan, Matthew C Kiernan, Michael eHornberger, Michael eHornberger, Michael eHornberger, Rachel H Tan, Rachel H Tan   +13 more
core   +2 more sources

White matter tract damage in the behavioral variant of frontotemporal and corticobasal dementia syndromes.

PLoS ONE, 2014
The phenotypes of the behavioral variant of frontotemporal dementia and the corticobasal syndrome present considerable clinical and anatomical overlap.
Fernanda Tovar-Moll, Ricardo de Oliveira-Souza, Ivanei Edson Bramati, Roland Zahn, Alyson Cavanagh, Michael Tierney, Jorge Moll, Jordan Grafman   +7 more
doaj   +1 more source

Characterizing sexual behavior in frontotemporal dementia [PDF]

, 2015
Background: Frontotemporal dementia (FTD) is characterized by a number of prominent behavioral changes. While FTD has been associated with the presence of aberrant or unusual sexual behaviors in a proportion of patients, few studies have formally ...
Ahmed, Rebekah M., Dermody, Nadene, Hodges, John R., Irish, Muireann, Kaizik, Cassandra, Kiernan, Matthew C., Mioshi, Eneida, Piguet, Olivier   +7 more
core   +1 more source

Mutant Tau knock-in mice display frontotemporal dementia relevant behaviour and histopathology [PDF]

, 2016
Peer ...
Drever, Benjamin D., Koss, David J., Platt, Bettina, Plucinska, Kaja, Riedel, Gernot, Robinson, Lianne, Stoppelkamp, Sandra, Veselcic, Peter   +7 more
core   +3 more sources

Frontotemporal Dementia: A Clinical Review

Journal of Education, Health and Sport
Frontotemporal dementia is a disease in which atrophic changes occur in the frontal lobes and frontal temporal lobes of the brain. Frontotemporal dementias are a clinically, neuroanatomically and pathologically diverse group of diseases that ...
Michał Dacka, Mikołaj Porzak, Karol Bochyński, Konrad Białogłowski, Paulina Dąbrowska, Michał Żuber, Katarzyna Ciuba, Katarzyna Molenda, Filip Borodziuk, Barbara Borodziuk   +9 more
doaj   +1 more source

Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum [PDF]

, 2005
In contrast to the common and genetically complex senile form of Alzheimer's disease (AD), the molecular genetic dissection of inherited presenile dementias has given important mechanistic insights into the pathogenesis of degenerative brain disease ...
Cruts, Marc, Dermaut, Bart, Kumar-Singh, Samir, Rademakers, Rosa, Theuns, Jessie, Van Broeckhoven, Christine   +5 more
core   +1 more source