Results 41 to 50 of about 92,917 (264)

Systemic Sarcoidosis Mimicking a Behavioural Variant of Frontotemporal Dementia

Case Reports in Neurological Medicine, 2015
Among rare neurological manifestations, a progressive dementia may exceptionally be the revealing clinical feature of a sarcoidosis. Diagnosis may then be difficult, especially when systemic signs are missing or latent, with a risk of therapeutic delay ...
Anne De Maindreville, Line Bedos, Serge Bakchine   +2 more
doaj   +1 more source

Neurosyphilis Initially Misdiagnosed as Behavioral Variant Frontotemporal Dementia: Life-Changing Differential Diagnosis

Journal of Alzheimer's Disease Reports, 2023
Diagnosing neurosyphilis can be challenging and it may be misdiagnosed as behavior variant frontotemporal dementia, given its affinity for the frontal and temporal lobes.
Michitaka Funayama, Shin Kuramochi, Shun Kudo   +2 more
doaj   +1 more source

Frontotemporal dementia: the impact of patient behavioral symptoms on the physical and mental health of family caregivers. [PDF]

, 2012
BackgroundProviding informal support to someone with frontotemporal dementia (FTD) could be very stressful. Clarifying the relationship between patient behavioral problems and caregiver health could spur future research on effective symptom management ...
Wallhagen, Margaret I, Wong, Cindy C
core   +3 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Altered Time Awareness in Dementia

Frontiers in Neurology, 2020
Our awareness of time, specifically of longer intervals spanning hours, days, months, and years, is critical for ensuring our sense of self-continuity.
Maï-Carmen Requena-Komuro, Charles R. Marshall, Charles R. Marshall, Rebecca L. Bond, Lucy L. Russell, Caroline Greaves, Katrina M. Moore, Jennifer L. Agustus, Elia Benhamou, Harri Sivasathiaseelan, Chris J. D. Hardy, Jonathan D. Rohrer, Jason D. Warren   +12 more
doaj   +1 more source

Neural Substrates of Semantic Prospection – Evidence from the Dementias [PDF]

, 2016
The ability to envisage personally relevant events at a future time point represents an incredibly sophisticated cognitive endeavor and one that appears to be intimately linked to episodic memory integrity.
Abraham, Addis, Addis, Addis, Andelman, Andersson, Andersson, Ashburner, Botzung, Claire O’Callaghan, Cooper, Dermody, Duval, D’Argembeau, Frisch, Greenberg, Hassabis, Hornberger, Irish, Irish, Irish, Irish, Irish, Irish, Irish, Irish, Irish, Irish, John R. Hodges, Karantoulis, Karas, Klein, Klein, Klein, Kwan, Manning, McKhann, Mechelli, Michael Hornberger, Mioshi, Mioshi, Morris, Muireann Irish, Mullally, Mullally, Nadene Dermody, Nadine Eyre, Nichols, Okuda, Olivier Piguet, Piolino, Race, Race, Rascovsky, Reitan, Rey, Rosen, Rueckert, Savage, Schacter, Schacter, Schacter, Schmidt, Smith, Smith, Squire, Strauss, Suddendorf, Szpunar, Szpunar, Wechsler, Westmacott, Zhang   +72 more
core   +2 more sources

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

The neural correlates and clinical characteristics of psychosis in the frontotemporal dementia continuum and the C9orf72 expansion

NeuroImage: Clinical, 2017
Objective: This present study aims to address the gap in the literature regarding the severity and underlying neural correlates of psychotic symptoms in frontotemporal dementia with and without the C9orf72 gene expansion. Methods: Fifty-six patients with
Emma M Devenney, Ramon Landin-Romero, Muireann Irish, Michael Hornberger, Eneida Mioshi, Glenda M. Halliday, Matthew C. Kiernan, John R. Hodges   +7 more
doaj   +1 more source

How preserved is emotion recognition in Alzheimer disease compared with behavioral variant frontotemporal dementia? [PDF]

, 2015
Background: Emotion deficits are a recognised biomarker for behavioural variant frontotemporal dementia (bvFTD), but recent studies have reported emotion deficits also in Alzheimer’s disease (AD).
Bertoux, Blennow, de Souza, Dubois, Elamin, Luzzi, Miller, Tapiola   +7 more
core   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source