Results 31 to 40 of about 161,801 (298)

Melanoma on Chronically Sun-Damaged Skin: Deciphering Gene Expression Signatures

Dermatology Practical & Conceptual
Introduction: Melanoma of the skin is responsible for most skin cancer-related deaths. It is well known that exposure to ultraviolet radiation is the most common and modifiable risk factor for melanoma.  Melanomas arising on chronically sun-damaged skin
Alejandra Avila, Varsha Thakur, Natalie Vincent, Pilar Valencia, Mecker Möller, Rimpi Khurana, Guo Yan, Jennifer C. Tang, Barbara Bedogni, Natalia Jaimes   +9 more
doaj   +1 more source

Integration of a Frost Mortality Scheme Into the Demographic Vegetation Model FATES

Journal of Advances in Modeling Earth Systems, 2023
Frost is damaging to plants when air temperature drops below their tolerance threshold. The set of mechanisms used by cold‐tolerant plants to withstand freezing is called “hardening” and typically take place in autumn to protect against winter damage ...
Marius S. A. Lambert, Hui Tang, Kjetil S. Aas, Frode Stordal, Rosie A. Fisher, Jarle W. Bjerke, Jennifer A. Holm, Frans‐Jan W. Parmentier   +7 more
doaj   +1 more source

A Review of Methods and Techniques for Detecting Frost on Plant Surfaces

Agriculture, 2021
Severe frost usually has adverse impacts on agricultural production, resulting in crop freeze injury, poor crop yield, and crop quality reduction. Timely and accurate detection of frost plays an important role in cold damage warnings, prevention, and ...
Huan Song, Yongguang Hu, Yongzong Lu, Jizhang Wang, Qingmin Pan, Pingping Li   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Activation of NPY2R-expressing amygdala neurons inhibits itch behavior in mice without lateralization

Scientific Reports
The central amygdala (CeA) is a crucial hub in the processing of affective itch, containing a diverse array of neuronal populations. Among these components, Neuropeptide Y (NPY) and its receptors, such as NPY2R, affect various physiological and ...
Darya Pavlenko, Zeynep Gizem Todurga-Seven, Kristen Sanders, Anika Markan, Rebecca Verpile, Hirotake Ishida, Dylan Costo, Tasuku Akiyama   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

“Frost Thistles.” [PDF]

Nature, 1917
n ...
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Avaliação de métodos para quantificar geada em evaporadores de refrigeradores frost-free [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Mecânica, Florianópolis, 2015.Em evaporadores no-frost o acúmulo de geada é inevitável.
Sette, Renata Cristina
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source