Results 41 to 50 of about 17,056 (260)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Estimation of Frost Hazard for Tea Tree in Zhejiang Province Based on Machine Learning

Agriculture, 2021
Tea trees are the main economic crop in Zhejiang Province. However, spring cold is a frequent occurrence there, causing frost damage to the valuable tea buds. To address this, a regional frost-hazard early-warning system is needed.
Jie Xu, Suri Guga, Guangzhi Rong, Dao Riao, Xingpeng Liu, Kaiwei Li, Jiquan Zhang   +6 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Peanut Frostbite Detection Method Based on Near Infrared Hyperspectral Imaging Technology

Shipin gongye ke-ji
Peanuts were susceptible to frost damage during harvesting, transportation, storage, and processing due to temperature and humidity changes, which could affect the quality of peanuts and their products.
Cheng CUI, Cuiling LIU, Xiaorong SUN, Jingzhu WU   +3 more
doaj   +1 more source

Frost Damage Increased by the Windbreak

Journal of Agricultural Meteorology, 1977
A large orchard of satsuma mandarin located nearest the sea coast of the southern end of Kyushu was completely destroyed by the early frost on the two successive nights in November, 1968. The orchard of 72 hectare area in an artificially flattened dune, 5m above sea level, is divided into 60 rectangular sections; each section, 100m wide and 120m long ...
MIHARA, Y., TSURUTA, K., NEMOTO, O.
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Determination of Late Spring Frost Affections on Some Grape Varieties Grown in Samsun

Türkiye Tarımsal Araştırmalar Dergisi, 2014
Determining the climatic factors of viticultural areas have great importance. The late spring frost cause significant amount of economic losses in some years in many of areas. In March and April of 2014 has experienced frost damage in many parts of our
Bülent KÖSE, Seda ATEŞ, Hüseyin ÇELİK   +2 more
doaj  

Experimental study on the evolution mechanism of compressive damage for frost-damaged rubberized concrete

Polymer Testing
The robust constitutive models and design guidelines of frost-damaged rubberized concrete support a green, low-carbon, and efficient construction practice.
Xiaoyan Han, Zhaoyan Bai, Dubo Wang, Aijiu Chen, Zhihao Wang, Lingyun Feng, Yanting Ji, Jinliang Jing, Keliang Li, Xiaozhou Xia, Qing Zhang, Linhua Jiang   +11 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source