Results 41 to 50 of about 2,296,255 (298)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A qualitative sequential frost deicing salt damage model on experimental data
, 2002 Frost and frost deicing salt resistance of cementitious materials has been the subject of numerous research projects during the past decades. Hence a large number of different frost and frost deicing salt damage mechanisms are proposed. Nevertheless none
Kaufmann, J.P. (author)
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Frost resistance of F-concrete
, 1987 Freeze-thaw tests and frost-salt tests were carried out for evaluating the frost resistance of F-concrete. Porosity and microstructural studies were included in the lest programme.
Vesikari, Erkki
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Microstructure and life prediction model of steel slag concrete under freezing-thawing environment
Nanotechnology Reviews, 2021 The goals of this paper are to study the frost resistance of steel slag concrete (SSC), research the damage mechanisms, and predict the service life of SSC in cold regions.
Wen Yang +7 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Морозостойкость рекомбинантно-инбредных линий пшеницы и ее связь с аллелями микросателлитных локусов
Фактори експериментальної еволюції організмів, 2014 Aim. The study of the relation between allelic differences of microsatellite loci and frost resistance of recombinant-inbred lines Luzanovka odesskaya/Odesskaya krasnokolosaya. Methods. Polymerase chain reaction (PCR), gel-electrophoresis, test of frost
М. В. Галаева +4 more
doaj
Advances in Civil Engineering, 2020 The reasonable inclusion of hybrid fibers can leverage the advantages of each kind of fiber and enhance the frost resistance and flexural toughness of concrete.
Daming Luo, Yan Wang, Ditao Niu
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source