Results 61 to 70 of about 2,296,255 (298)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Journal of Civil Engineering and Management, 2000 Up today in Europe there is no unanimous opinion which method is necessary for a correct assessment of roof ceramic tile frost resistance corresponding to the climatic conditions of application.
Antanas Sadūnas +4 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Experimental Research on Frost Indexes for Lycium Barbarum Flowering Phase
应用气象学报, 2020 Based on researches of frost indexes of Lycium barbarum during 2016-2018, tests of frost index are performed using an artificial frost box in 2019, focusing on flower bud, early flowering and full flowering periods. The temperature of treatment is -8—-1℃,
Duan Xiaofeng +5 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Фактори експериментальної еволюції організмів, 2015 Aim. To carry through selections in artificial conditions by frost resistance among early generations of winter wheat hybrids (F2 – F4) and to verify their effectiveness in later generations (F5 – F6). Methods.
В. В. Кириленко +5 more
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Effects of surface states on salt-frost scaling resistance of cement concrete
Case Studies in Construction Materials, 2019 This study discussed influences of surface states of concrete on salt-frost durability. By using the Capillary suction of Deicing solution and Freeze-thaw test method(CDF), the effects of factors, such as solution saturation in capillary, surface ...
Hui Zhang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Selection for frost resistance in Coffea arabica progenies carrying C. liberica var. dewevrei genes
Crop Breeding and Applied Biotechnology, 2005 This research was carried out to estimate the variability and genetic parameters for the development of cultivars more frost resistant in Coffea arabica progenies, carrying C. liberica var. dewevrei genes.
Marcos Rafael Petek +2 more
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