O-206 Natural, modified natural or artificial endometrial preparation strategies for frozen embryo transfer in ovulatory women (MONART): a randomized controlled trial [PDF]
Vu N A Ho +7 more
openalex +1 more source
Deferring embryo transfer of morula and early blastocysts on day 5 improves implantation rates when these embryos are cultured to day 6, vitrified at advanced stage and transferred after warming in frozen embryo transfer (fet) cycles [PDF]
, 2016 Cathy Dowling +5 more
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Advanced Science, EarlyView.This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong +6 more
wiley +1 more source
The Impact of L-Arginine on Uterine Artery Resistance and Pregnancy Outcomes in Frozen Embryo Transfer for IVF Candidates with Recurrent Implantation Failure: A Clinical Trial [PDF]
Faezeh Fazli +2 more
openalex +1 more source
Advanced Science, EarlyView.We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques
Advanced Science, EarlyView.Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang +12 more
wiley +1 more source
Bone mineralization in children aged 7–10 years born after ART with frozen and fresh embryo transfer [PDF]
Elisabeth Waldemar Grønlund +7 more
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Advanced Science, EarlyView.We investigate by proteomics studies how strand‐symmetric and ‐asymmetric cytosine 5‐modifications in DNA are selectively recognized by the nuclear proteome. Using promoter probes with defined modification patterns, we identify tissue‐specific reader proteinsincluding MYC, MAX, and RFX5that discriminate 5‐hydroxymethylcytosine symmetry and sequence ...
Lena Engelhard +8 more
wiley +1 more source
Advanced Science, EarlyView.Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang +16 more
wiley +1 more source