Results 41 to 50 of about 386,963 (256)

Frozen Section Quality Assurance

American Journal of Clinical Pathology, 2021
Abstract Objectives Composite frozen section turnaround time has limited value, precluding assessment of certain processes: slide preparation (technical) and diagnosis (interpretation). We examined whether measuring these elements could identify delays, hypothesizing that longer times were related to (
Joseph M, Laakman, Stephanie J, Chen, Kim S, Lake, John L, Blau, D Anand, Rajan, Megan I, Samuelson, Robert A, Robinson   +6 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Frozen Section Versus Permanent Section in Cancer Diagnosis: A Single Centre Study

Asian Pacific Journal of Cancer Care, 2022
Introduction: Frozen section is an intraoperative pathological technique which has very important role to play in diagnostics and also it plays important role in futher surgical management as specially in oncology setup.
Barasha Sarma Bharadwaj, Muktanjalee Deka, Manisha Salvi, B K Das, B C Goswami   +4 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Enhancing frozen histological section images using permanent-section-guided deep learning with nuclei attention

Scientific Reports
In histological pathology, frozen sections are often used for rapid diagnosis during surgeries, as they can be produced within minutes. However, they suffer from artifacts and often lack crucial diagnostic details, particularly within the cell nuclei ...
Elad Yoshai, Gil Goldinger, Tatiana Kogan, Anna Zakharov, Miki Haifler, Natan T. Shaked   +5 more
doaj   +1 more source

Evaluating Diagnostic Accuracy: Frozen and Permanent Sections

Journal of Nature and Science of Medicine
Context: Frozen section (FS) analysis is an intraoperative diagnostic approach that provides surgeons with timely information to guide immediate clinical decisions. Aims: The aim of this study was to evaluate the diagnostic accuracy, turnaround time (TAT)
Mohammed A. Alswayyed, Saeed O. Bahabri, Malak A. Alzahrani, Ahmad R. Almotairi, Tamadar Al Doheyan, Hisham M. Alkhalidi, Ahmed A. Alhumidi, Amany A. Fathaddin, Wajd A. Althakfi, Fadi S. Alakeel, Maria A. Arafah   +10 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Comparison of pre- and postoperative parathyroid hormone levels with frozen section during parathyroidectomy

The Journal of Qazvin University of Medical Sciences, 2015
Background: Due to the short half-life of parathyroid hormone (PTH), intra-operative quick PTH measurement (immediately after removal of adenoma) is beneficial to identify and evaluate the adequacy of tissue removal and to reduce reoperation and more ...
H. Parsa, M. Samimifar
doaj