Results 71 to 80 of about 825,067 (293)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Enhancing frozen histological section images using permanent-section-guided deep learning with nuclei attention

Scientific Reports
In histological pathology, frozen sections are often used for rapid diagnosis during surgeries, as they can be produced within minutes. However, they suffer from artifacts and often lack crucial diagnostic details, particularly within the cell nuclei ...
Elad Yoshai, Gil Goldinger, Tatiana Kogan, Anna Zakharov, Miki Haifler, Natan T. Shaked   +5 more
doaj   +1 more source

Evaluating Diagnostic Accuracy: Frozen and Permanent Sections

Journal of Nature and Science of Medicine
Context: Frozen section (FS) analysis is an intraoperative diagnostic approach that provides surgeons with timely information to guide immediate clinical decisions. Aims: The aim of this study was to evaluate the diagnostic accuracy, turnaround time (TAT)
Mohammed A. Alswayyed, Saeed O. Bahabri, Malak A. Alzahrani, Ahmad R. Almotairi, Tamadar Al Doheyan, Hisham M. Alkhalidi, Ahmed A. Alhumidi, Amany A. Fathaddin, Wajd A. Althakfi, Fadi S. Alakeel, Maria A. Arafah   +10 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Comparison of pre- and postoperative parathyroid hormone levels with frozen section during parathyroidectomy

The Journal of Qazvin University of Medical Sciences, 2015
Background: Due to the short half-life of parathyroid hormone (PTH), intra-operative quick PTH measurement (immediately after removal of adenoma) is beneficial to identify and evaluate the adequacy of tissue removal and to reduce reoperation and more ...
H. Parsa, M. Samimifar
doaj  

Pion wave functions from holographic QCD and the role of infrared renormalons in photon-photon collisions

, 2012
In this article, we calculate the contribution of the higher-twist Feynman diagrams to the large-$p_T$ inclusive single pion production cross section in photon-photon collisions in case of the running coupling and frozen coupling approaches within ...
A. Erdelyi, A. I. Ahmadov, C. Aydin, E. Witten, F. Cornet, F. Keskin, G.’t. Hooft, J. M. Maldacena, S. Furui, S. J. Brodsky, W. Greiner   +10 more
core   +1 more source

Measurements of polarized photo-pion production on longitudinally polarized HD and Implications for Convergence of the GDH Integral [PDF]

, 2008
We report new measurements of inclusive pion production from frozen-spin HD for polarized photon beams covering the Delta(1232) resonance. These provide data simultaneously on both H and D with nearly complete angular distributions of the spin-difference
A. Caracappa, A. D’Angelo, A. d’Angelo, A. Fantini, A. Honig, A. Lehmann, A. M. Sandorfi, A. M. Sandorfi, B. Norum, B. Preedom, C. Bade, C. E. Thorn, C. Gibson, C. S. Whisnant, C. Schaerf, D. Moricciani, H. Glückler, H. Seyfarth, H. Ströher, J. Ahrens, J. Mahon, K. Ardashev, K. Hicks, K. Wang, L. Miceli, M. Blecher, M. Khandaker, M. Lowry, M. Lucas, M. Pap, O. Bartalini, O. C. Kistner, R. Di Salvo, S. Hoblit, S. Kizilgul, S. Kucuker, S. B. Gerasimov, T. Kageya, X. Wei   +38 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Studies of differential and total photoionization cross sections of carbon dioxide [PDF]

, 1982
The photoionization of CO2 has been studied using accurate frozen-core Hartree-Fock final-state wave functions. The Hartree-Fock continuum equations were solved using the iterative Schwinger variational method.
Lucchese, Robert R., McKoy, Vincent
core   +1 more source