Results 81 to 90 of about 199,191 (301)
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Lowering Sperm Dose Rates in Frozen Semen for Bovine Artificial Breeding
The New Zealand Dairy industry relies on artificial breeding to produce high genetic merit replacement stock. Proven bull semen is extended and preserved as either ambient temperature product or as frozen doses.
Pitt, Colin John
core
PHYSICAL CHANGES OF TILAPIA FISH BURGER DURING FROZEN STORAGE
The effects of frozen storage on weight loss during freezing, cooking yield, dimensional changes, and instrumental texture parameters of tilapia fish burger were evaluated during 6 months.
Corazza, Marcos L. +3 more
core +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Antioxidants in fresh and frozen fruit and vegetables: Impact study of varying storage conditions [PDF]
Antioxidants and other key nutritional components of food are known to be affected by factors such as handling and storage conditions. The purpose of this study was to evaluate the impact of storage conditions on a range of fresh and frozen fruit and ...
Bonwick GA, Birch C
core
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Fillets of herring (Clupea harengus) were kept on ice for 0, 3, 6, and 9 days prior to storage at −18 °C for 0, 21, 42, 63, and 84 days. At each storage point, peroxide value (PV), absorbance at 268 nm (A268), fluorescent products (FP), α-tocopherol ...
Lingnert, Hans +3 more
core +2 more sources
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Aims: Shelf life estimation, determination, and validation of frozen food are essential in HACCP and can be done by adopting an accelerated shelf life (ASL) study to reduce the time and cost of a long-lasting experiment.
Mahmud Ab Rashid, Nor-Khaizura +3 more
core +1 more source

