Results 51 to 60 of about 803 (166)

Specnuezhenide Ameliorates Age-Related Hepatic Lipid Accumulation via Modulating Bile Acid Homeostasis and Gut Microbiota in D-Galactose-Induced Mice

open access: yesMetabolites, 2023
Age-related hepatic lipid accumulation has become a major health problem in the elderly population. Specnuezhenide (SPN) is a major active iridoid glycoside from an edible herb Fructus Ligustri Lucidi, which is commonly used for preventing age-related ...
Xuehui Deng   +4 more
doaj   +1 more source

Fructus ligustri lucidi suppresses inflammation and restores the microbiome profile in murine colitis models

open access: yesPhytomedicine, 2022
Ulcerative colitis (UC) is pathologically characterized by an inappropriate immune response to the gut commensal microbes accompanied by persistent epithelial barrier dysfunction, and its progression increases the susceptibility to colitis-associated cancer (CAC), as well as other complications.
Wei Yu   +6 more
openaire   +2 more sources

Targeting cellular senescence in senile osteoporosis: therapeutic potential of traditional Chinese medicine

open access: yesFrontiers in Medicine, 2023
Senile osteoporosis (SOP) is a prevalent manifestation of age-related bone disorders, resulting from the dysregulation between osteoblast (OB)-mediated bone formation and osteoclast (OC)-mediated bone resorption, coupled with the escalating burden of ...
Yingyi Zhang   +8 more
doaj   +1 more source

Improvement of bone properties and enhancement of mineralization by ethanol extract of Fructus Ligustri Lucidi [PDF]

open access: yesBritish Journal of Nutrition, 2008
Fructus Ligustri Lucidi (FLL), a kidney-tonifying Chinese herb, was shown to regulate Ca balance in ovariectomized (OVX) rats in our previous study. This study investigated whether it could improve bone properties in aged normal and OVX rats and increase osteoblastic differentiation in rat osteoblast-like UMR-106 cells.
Zhang, Y   +5 more
openaire   +3 more sources

Phytotherapy for the Treatment of Glioblastoma: A Review

open access: yesFrontiers in Surgery, 2022
BackgroundPhytotherapy; the study of extracts of natural origin in the treatment of disease, has scarcely been applied in the management of GBM. A body of literature exists studying in-vitro, the use of natural extracts against GBM cells.
Shan Yasin Mian   +2 more
doaj   +1 more source

Anti-diabetic activity of aqueous extract of Fructus Ligustri Lucidi in a rat model of type 2 diabetes

open access: yes, 2018
Purpose: To determine the anti-diabetic activity of an aqueous extract of Fructus Ligustri Lucidi (FLL) in a rat model of type 2 diabetes (T2D).Method: Body weight (BW), food intake (FI), fasting blood glucose (FBG), glucose tolerance testing and insulin
Cao, Lanxiu   +3 more
core   +2 more sources

Identification of Critical Biomarkers and Mechanisms of Fructus Ligustri Lucidi on Vitiligo Using Integrated Bioinformatics Analysis

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Tian-Shan Liang,1,* Nan Tang,1,* Ming-Hua Xian,2 Wei-Lun Wen,1 Chang-Jin Huang,1 Lan-Hua Cai,1 Qi-Lin Li,3 Yan-Hua Wu1 1Department of Traditional Chinese Medicine, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, Guangdong, 510220 ...
Liang TS   +7 more
doaj  

Chemical composition and glucose uptake effect on 3T3-L1 adipocytes of Ligustrum lucidum Ait. flowers

open access: yesFood Science and Human Wellness, 2020
Ligustri lucidi Fructus is a traditional Chinese medicine and possesses various bioactivities, including hypoglycemic effect. Ligustrum lucidum Ait flowers are poorly investigated. Thus, we hypothesized that L.
Lili Cui   +6 more
doaj   +1 more source

Effects of the combined extracts of Herba Epimedii and Fructus Ligustrilucidi on airway remodeling in the asthmatic rats with the treatment of budesonide

open access: yesBMC Complementary and Alternative Medicine, 2017
Background Asthma is characterized by chronic airway inflammation, leading to structura1 changes in the airway, collectively termed airway remodeling.
Xiufeng Tang   +8 more
doaj   +1 more source

Integrating mass spectrometry and systems biology for the modernization of natural medicines: From deciphering chemical complexity to holistic efficacy assessment

open access: yesVIEW, Volume 7, Issue 2, April 2026.
This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu   +7 more
wiley   +1 more source

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